Mevion nabs FDA OK for proton therapy system

Mevion Medical Systems has received 510(k) clearance from the U.S. Food and...Read more on AuntMinnie.comRelated Reading: Mevion submits 510(k) to FDA for proton therapy system Mevion touts scanning milestone Mevion joins forces with MedPhoton Mevion completes milestone installation Mevion completes Fla. installation
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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In this study, we aim to show the feasibility of 4D treatment planning for pencil beam scanning (PBS) proton therapy of pancreatic cancer, based on repeated 4DMRI datasets and 4D dose calculations (4DDC). To investigate the dosimetric impacts of organ motion, deformation vector fields were extracted from 4DMRI, which were then used to warp a static CT of a patient, so as to generate synthetic 4DCT (4DCT-MRI). The results from 4DDC show pronounced interplay effects in the CTV with dose homogeneity d5/d95 and dose coverage v95 being 1.14 and 91%, respectively, after a single fraction of the treatment. An averaging effec...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
In conclusion, an automated, easy-to-use Monte Carlo calculation system has been set up. This system reproduced patient specific QA results over a wide range of cases, showing that the time consuming measurements could be reduced or even replaced using Monte Carlo simulations without jeopardizing treatment quality. PMID: 30010613 [PubMed - as supplied by publisher]
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
Mevion Medical Systems has secured $150 million in financing in a deal...Read more on AuntMinnie.comRelated Reading: Mevion treats 1st patient with proton therapy system Mevion nabs FDA OK for proton therapy system Mevion submits 510(k) to FDA for proton therapy system Mevion touts scanning milestone Mevion joins forces with MedPhoton
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
In conclusion, this work shows that the INSIDE in-beam PET scanner performance is promising towards its in-vivo test with carbon ions. PMID: 29873299 [PubMed - as supplied by publisher]
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
This study's purpose is to develop and evaluate an automated method for adaptation of IMPT plans in near real-time to the anatomy of the day. We developed an automated treatment plan adaptation method using (1) a restoration of spot positions (Bragg peaks) by adapting the energies to the new water equivalent path lengths; and (2) a spot addition to fully cover the target of the day, followed by a fast Reference Point Method optimization of the spot weights resulting in a Pareto optimal plan for the daily anatomy. The method was developed and evaluated using 8-10 repeat CT scans of 11 prostate cancer patients, prescrib...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
Conclusions Our data demonstrate that a carbon composite fiducial has a less untoward effect on proton therapy dose distribution than dedicated EUS pre-loaded gold fiducial needles. Such information is important to consider when selecting fiducials specifically for proton therapy. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Concepts of planning target volume and plan robustness in proton therapy are described. Implementation of these concepts into treatment planning is described. Proton plan sensitivity and interfractional and intrafractional anatomical variation are also discussed.
Source: Seminars in Radiation Oncology - Category: Cancer & Oncology Authors: Source Type: research
Proton therapy (PT) is an increasingly utilized radiation treatment in alternative to photon therapy for malignancies of the breast [1]. The main motivation for the use of protons lies in the potential reduction of radiation-induced side effects such as cardiac toxicity (especially for left-side breast patients), pulmonary toxicity and induction of secondary cancers [2 –4]. PT could be particularly advantageous in the irradiation of breast gland plus internal mammary lymph nodes, due to the complex irradiation geometry [5].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research
1224Aim:Radeation therapy (RT) is an important component of cancer treatment for both early stage and locally advanced lung cancers. Photon and proton therapies are both utilized for RT but have different physical characteristics. Photon RT actively exposes healthy tissues along the beam path in front of and beyond the tumor to incidental irradiation. However, due to a central-axis depth-dose distribution pattern known as the spread-out Bragg peak (SOBP), proton RT generally has a more optimal dose delivery in comparison to 3D conformal photon therapy and intensity-modulated radiation therapy (IMRT). The SOBP may potential...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Educational Exhibits Source Type: research
Conclusions: Despite the often-complicated geometry and the high washout, it is possible to use profiles to compare measured and expected range differences of proton treatments in the head. We are able to provide an assessment of range differences between PET and MC-PET, and thus planned and delivered dose, across the entire beam cross section. The modified MC parameters for CSF regions made the profile shape of the MC more realistic and improved the comparison with PET. Results of the range comparisons can be used on a patient/fraction basis to check individual fractions, or population basis to determine the overall accur...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Image Guided Therapy Source Type: research
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