ACR calls for summer radiology internship applications

The American College of Radiology (ACR) is accepting applications from first-year...Read more on AuntMinnie.comRelated Reading: ACR revises Appropriateness Criteria ACR names 2018 gold medalists ACR releases breast cancer screening criteria ACR updates Appropriateness Criteria Hillman to step down as editor of JACR
Source: Headlines - Category: Radiology Source Type: news

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Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
New research investigates whether following a low-fat diet after being diagnosed with breast cancer improves the patient's outcome.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Breast Cancer Source Type: news
Breast cancer survivors aren't getting regular follow-up mammograms, according...Read more on AuntMinnie.comRelated Reading: Twitter hashtag war erupts over breast screening ASBrS: Regular mammo screening = less-invasive treatment ACR, SBI: Some black women need earlier breast screening Less isn't always more with breast screening recall rate Race matters for breast cancer screening protocols
Source: Headlines - Category: Radiology Source Type: news
The St Gallen International Expert Consensus Conference has issued new treatment recommendations for women with early-stage breast cancer and guidance for clinicians who manage this population.Annals of Oncology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news
AbstractX chromosome gain has been previously described in male breast cancer (MBC). Androgen receptor (AR) gene is located on X chromosome. The aim of this study was to investigate the role of the X chromosome gain in the development of MBC and its relation with AR gene copy number and expression.The X chromosome status was assessed in 66 cases of male invasive and in situ duct breast carcinoma, in 34 cases of gynecomastia associated with cancer, and in 11 cases of tumor-free gynecomastia. Cases were tested by fluorescence in situ hybridization (FISH) to assess the X chromosome status and AR amplification. AR expression w...
Source: Virchows Archiv - Category: Pathology Source Type: research
Connexin-43 (Cx43, also known as GJA1) is the most ubiquitously expressed connexin isoform in mammalian tissues. It forms intercellular gap junction (GJ) channels, enabling adjacent cells to communicate both electrically and metabolically. Cx43 is a short-lived protein which can be quickly degraded by the ubiquitin-dependent proteasomal, endolysosomal, and autophagosomal pathways. Here, we report that the ubiquitin-specific peptidase 8 (USP8) interacts with and deubiquitinates Cx43. USP8 reduces both multiple monoubiquitination and polyubiquitination of Cx43 to prevent autophagy-mediated degradation. Consistently, knockdow...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Protein Synthesis and Degradation Source Type: research
This study has clarified sex-hormone control by sulfatase in BC, suggesting that the different roles of estradiol and 5α-dihydrotestosterone can lead to a reduction in the effect of sulfatase inhibition when compared with 17β-HSD7 inhibition. This suggests that combined treatment of sulfatase inhibitors with 17β-HSD inhibitors such as the type7 inhibitor could hold promise for hormone-dependent breast cancer. Graphical abstract
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Source: Cancercompass News: Breast Cancer - Category: Cancer & Oncology Source Type: news
ee Dong-Chan Oh LC/MS-based chemical profiling of a ginseng farm soil-derived actinomycete strain, Streptomyces sp. BYK1371, enabled the discovery of two new cyclic heptapeptides, depsidomycins B and C (1 and 2), each containing two piperazic acid units and a formyl group at their N-terminus. The structures of 1 and 2 were elucidated by a combination of spectroscopic and chemical analyses. These new compounds were determined to possess d-leucine, d-threonine, d-valine, and S-piperazic acid based on the advanced Marfey’s method and a GITC (2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl isothiocyanate) de...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: Available online 24 May 2018 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Joëlle A.C. Desreux Breast cancer is the leading cause of death by cancer in women aged less than 40. However, organized screening of young healthy women has been recognized as inefficient and even deleterious by most experts [1], and should not been offered. Individualized screening, targeting only some young high-risk women, may be beneficial although no randomized trial has proven an impact on breast cancer mortality. All recommendations are based on expert’s opinions. Thi...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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