Impaired contraction of blood clots as a novel prothrombotic mechanism in systemic lupus erythematosus

In conclusion, autoantibodies in SLE can affect platelet contractility, resulting in reduced ability of clots and thrombi to shrink in volume, which increases vessel obstruction and may aggravate the course and outcomes of thrombotic complications in SLE.

Source: Clinical Science - January 2, 2018 Category: Biomedical Science Authors: Le Minh, G., Peshkova, A. D., Andrianova, I. A., Sibgatullin, T. B., Maksudova, A. N., Weisel, J. W., Litvinov, R. Tags: PublishAheadOfPrint Source Type: research