Lung cancer screening works better when individual risk factors are taken into account, study says

New research estimates that in a single year, some 5,000 lung cancer deaths might be averted if some former smokers who don ’t currently qualify for lung-cancer screening were to get a computed tomography scan capable of detecting malignancy.The U.S. Preventive Services Task Force, which lays down...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news

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Surgery is the gold standard treatment for operable patients with stage Ⅰ or Ⅱ non-small lung cancer (NSCLC) [1]. Stereotactic Body Radiation Therapy (SBRT) is an alternative treatment option for non-surgical T1-2N0 NSCLC patients [2–4]. Recent studies shows that non-surgical patients with stage Ⅰ NSCLC can be treated by SBRT with reasonable local control [5–7 ]. NSCLC with confirmed nodal metastasis (N1 or N2 disease) is usually an exclusion for SBRT. Nodal statuses are first assessed by radiological examination such as computed tomography (CT) and/or F-fluoro-2-deoxy-d-glucose (FDG)-positron emission tomography (PET).
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
Conclusions STS-GTSD participants performed invasive mediastinal staging more frequently than prior reports, and yet only in a minority of patients. Rates of invasive mediastinal staging vary widely across STS-GTSD participants.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Conclusion: Even though NF1 patients did not show an increased risk of thyroid incidentaloma on PET/CT compared to previous studies on non-thyroid cancer patients, the incidence shows that awareness of possible thyroid disease is important.Eur Thyroid J
Source: European Thyroid Journal - Category: Endocrinology Source Type: research
Abstract BACKGROUND: Prior studies suggest underutilization of invasive mediastinal staging for lung cancer. We hypothesized that Society of Thoracic Surgeons General Thoracic Surgery Database (STS-GTSD) participants would have higher rates of invasive staging compared to previous reports. METHODS: We conducted a retrospective cohort study (2012-2016) of lung cancer patients staged by computed tomography and positron-emission tomography and first treated with an anatomic resection. We defined invasive staging by the use of mediastinoscopy, endosonography, and/or thoracoscopy. Standardized incidence ratios (SI...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
ía Figueiras R, Alés Martínez JE Abstract Imaging in oncology is an essential tool for patient management but its potential is being profoundly underutilized. Each of the techniques used in the diagnostic process also conveys functional information that can be relevant in treatment decision making. New imaging algorithms and techniques enhance our knowledge about the phenotype of the tumor and its potential response to different therapies. Functional imaging can be defined as the one that provides information beyond the purely morphological data, and include all the techniques that make it pos...
Source: Radiologia - Category: Radiology Authors: Tags: Radiologia Source Type: research
The American Lung Association's Saved by the Scan campaign materials encourage patients to talk to their doctor but omit a vital piece of information: A CT scan comes with risk as well as benefit.Medscape Radiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Radiology Article Source Type: news
Authors: Abdelsattar ZM, Blackmon SH Abstract There are many novel technologies that enable complex segmentectomy to be performed. As lung cancer screening becomes more prevalent, patients are increasingly diagnosed with early stage lung cancer, multifocal disease, and second primary tumors. This shift to an earlier clinical presentation combined with advances in technology and an emphasis on minimally invasive techniques have led to the current developments we are now seeing with anatomic segmentectomy. In this paper, we describe the operative technique of an indocyanine green (ICG)-guided video-assisted thoracosc...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Authors: Suzuki K, Yanagimura T, Ohashi K, Kagamu H, Takada T Abstract A 65-year-old man was diagnosed with advanced non-small, non-squamous lung cancer. He was treated with chemotherapy containing bevacizumab as well as cisplatin and pemetrexed. After 2 courses of treatment, computed tomography revealed that his abdominal aortic artery was almost occluded by a thrombus; however, he had no ischemic symptoms. Heparin infusion and warfarin reduced the size of the arterial thrombus and the patient was subsequently treated with chemotherapy without bevacizumab. No thrombotic events occurred during the subsequent treatm...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
The objectives of this first-in-human study were to evaluate the safety, biodistribution and dosimetry of this αvβ6-directed imaging probe. Methods: [18F]αvβ6-BP was prepared per current good manufacturing practice (cGMP) under the guidelines of USP Chapter using N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) and the product was formulated in saline/ethanol (
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: First-in-Human & amp; New Human Applications Source Type: research
145Aim: Positron emission Tomography/Computed Tomography (PET/CT) with 18F-FAZA is a valuable non-invasive method to investigate tumour hypoxia. Aim of the present study is to investigate the likelihood of a correlation between 18F-FAZA imaging data and hypoxia immunohistochemical markers in patients with high-grade glioma (HGG) Patients and Methods. Prospective single Centre clinical study. Eighteen patients with brain MRI suggestive for HGG have been enrolled and underwent pre-treatment 18F-FAZA PET/CT (2/18: FAZA not performed for tracer synthesis failure). The following 18F-FAZA PET-derived parameters have been conside...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Neurooncology - Novel PET Approaches Source Type: research
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