Prenatal Maternal Serum Concentrations of Per- and Polyfluoroalkyl Substances in Association with Autism Spectrum Disorder and Intellectual Disability

Conclusions: Results from this large case–control study with prospectively collected prenatal measurements do not support the hypothesis that prenatal exposure to PFAS is positively associated with ASD or ID. https://doi.org/10.1289/EHP1830 Received: 28 February 2017 Revised: 22 November 2017 Accepted: 24 November 2017 Published: 2 January 2018 Address correspondence to K. Lyall, A.J. Drexel Autism Institute, 3020 Market St., Suite 560, Philadelphia, PA 19104-3734 USA. Telephone: (215) 571-3215. Email: kld98@drexel.edu *Current affiliation: McKesson Corporation, 1 Post St., San Francisco, CA 94104 USA. Supplemental Material is available online (https://doi.org/10.1289/EHP1830). The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Supplemental Material PDF (638 KB) Note to readers with disabilities: EHP has provided a 508-conformant table of contents summarizing the Supplemental Material for this article (see below) so readers with di...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

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ConclusionsStudents with ID are at increased risk of developing depressive symptoms when exposed to negative social relationships (i.e., peer victimization or TSR conflict). For these students, the benefits of TSR warmth were far less important than the consequences of conflict.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Publication date: Available online 16 January 2020Source: Nano EnergyAuthor(s): Xiaoling Ma, Jian Wang, Qiaoshi An, Jinhua Gao, Zhenghao Hu, Chunyu Xu, Xiaoli Zhang, Zhitian Liu, Fujun ZhangAbstractTernary strategy has been confirmed as an efficient method to improve the power conversion efficiency (PCE) of organic photovoltaics (OPVs). The 15.7% PCE is achieved from PM6:Y6 based binary OPVs. One nonfullerene acceptor Br-ITIC and fullerene derivative PC71BM are selected as the third component on the basis of efficient binary OPVs, respectively. The optimized ternary OPVs exhibit 16.4% and 16.2% PCE with Br-ITIC and PC71BM ...
Source: Nano Energy - Category: Nanotechnology Source Type: research
Publication date: Available online 16 January 2020Source: Materials Today: ProceedingsAuthor(s): Elena LacatusAbstractThe flexible functionalized graphene-based auxetic nanostructures are freely adapting the wave fields while their phase and amplitude being entirely controlled by design. Computer modelling can be used to define a biocompatible unit-module, as a GO-composite bilayer able to mimic the relationship between the structural composition of the skin and its response to bio-electro-magnetically stimuli. The selective response of the excited system simulates the functional behaviour of the model unit volume, the ski...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Publication date: Available online 16 January 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Victoria S. Marshe, Farhana Islam, Malgorzata Maciukiewicz, Laura M. Fiori, Volodymyr Yerko, Jennie Yang, Gustavo Turecki, Jane A. Foster, Sidney H. Kennedy, Daniel M. Blumberger, Jordan F. Karp, James L. Kennedy, Benoit H. Mulsant, Charles F. Reynolds, Eric J. Lenze, Daniel J. MüllerAbstractBackgroundMicroRNAs (miRNAs) are small 22 nucleotides long, non-coding RNAs that are potential biomarkers for antidepressant treatment response. We aimed to replicate previous associations of miRNAs wi...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
ConclusionsDue to its pro-cognitive effects and faster antidepressant effect, serial ketamine administration might be a more favorable short-term treatment option than ECT.LimitationsAs this research employed a naturalistic study design, patients were not systematically randomized, there was no control group and patients received concurrent and partially changing medications during treatment.Clinical trials registrationFunctional and Metabolic Changes in the Course of Antidepressive Treatment, https://clinicaltrials.gov/ct2/show/NCT02099630, NCT02099630.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Conclusions: Sleep patterns in children and adolescents were related to the psychiatric diagnosis of their parent(s). Future follow-up of these results may clarify the relations between early sleep differences and the risk of developing mood disorders in individuals at high familial risk.IntroductionSleep disturbances are core symptoms of mood disorders including major depressive disorder and bipolar disorder (1). Additionally, sleep problems have been associated with more severe symptoms, greater functional impairment, and increased risk for relapse among individuals with mood disorders (2). Over 40% of children and youth...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: We concluded there was sufficient evidence supporting an association between developmental PBDE exposure and reduced IQ. Preventing developmental exposure to PBDEs could help prevent loss of human intelligence. https://doi.org/10.1289/EHP1632 Received: 16 January 2017 Revised: 28 April 2017 Accepted: 28 April 2017 Published: 03 August 2017 Address correspondence to J. Lam, Program on Reproductive Health and the Environment, University of California, San Francisco, Mail Stop 0132, 550 16th St., 7th floor, San Francisco, CA 94143 USA. Telephone: (415) 476-3219. Email: Juleen.Lam@ucsf.edu Supplemental Materi...
Source: EHP Research - Category: Environmental Health Authors: Tags: Review Source Type: research
Conclusion: Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort, and some associations were stronger among boys. https://doi.org/10.1289/EHP984 Received: 18 August 2016 Revised: 09 December 2016 Accepted: 12 December 2016 Published: 16 June 2017 Address correspondence to Joseph M. Braun, Department of Epidemiology, Box G-S121-2, Brown University, Providence, RI 02912 USA. Telephone: (401) 863-5397. E-mail: joseph_braun_1@brown.edu Supplemental Material is available online (https://doi.org/10.1289/EHP984). The authors declare they have no actual or potential competing fi...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusions: This study identified potential relationships between maternal residential proximity to agricultural use of neurotoxic pesticides and poorer neurodevelopment in children. https://doi.org/10.1289/EHP504 Received: 08 January 2016 Revised: 13 May 2016 Accepted: 14 June 2016 Published: 25 May 2017 Address correspondence to R. Gunier, Center for Environmental Research and Childrens Health (CERCH), School of Public Health, University of California at Berkeley, 1995 University Ave., Suite 265, Berkeley, CA 94704. Telephone: (510) 847-3858. E-mail: gunier@berkeley.edu. A.B. is a volunteer member of the Board for...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusion: Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141–148; http://dx.doi.org/10.1289/EHP299 Address correspondence to F.P. Perera, Department of Environmental Health Sciences, Columbia Center for Children’s Environmental Health, Columbia University Mailman School of Public Health, 722 West 168th St. ...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentaries Children's Health February 2017 Source Type: research
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