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Fractional Exhaled NO Moderately Accurate to Diagnose Asthma

FeNO measurement performs better in diagnosing non - smokers, children, and steroid - naive patients
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nursing, Pediatrics, Pulmonology, Journal, Source Type: news

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Conclusion and Clinical Relevance: In mild asthmatics, there was a significant upregulation of ST2 surface expression on eosinophils from blood and sputum following allergen inhalation challenge. In vitro, IL-33 stimulation of eosinophils increases both ST2 membrane expression and IL-5 production. These results support a role for IL-33 in causing allergen-induced eosinophilia. Blockade of IL-33 and ST2 signaling may present a novel therapeutic avenue for asthma treatment.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewChronic sinus and upper airway disease in children is a common health problem encountered every day. Its pathophysiology is complicated which leads to different treatment options and approaches. We seek to review the current literature and evidence to surgical treatments.Recent FindingsMedical treatment with antibiotics and topical nasal sprays continues to be the first-line treatment. Surgical interventions include adenoidectomy, balloon catheter sinuplasty (BCS), and endoscopic sinus surgery (ESS). Each modality has proven to be safe; however, its effectiveness is widely variable.SummaryMore rese...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
A robust new study out of Taiwan has found evidence that people who suffer from allergies are more likely to develop a psychiatric
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This World Allergy Week (April 22 - 28) and World Asthma Day (May 1), Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, is helping parents take charge of their children's asthma and allergy symptoms through awareness initiatives in more than 20 countries worldwide.
Source: eHealth News EU - Category: Information Technology Tags: Featured Philips Business and Industry Source Type: news
Bronchial epithelial interferon- α/β protein expression was deficient in asthma. Lower epithelial interferon-α/β production was associated with adverse clinical outcomes following rhinovirus infection in vivo. Boosting deficient anti-viral immunity in asthma would likely ameliorate exacerbations.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Stratification of patients with severe asthma by blood eosinophil counts predicts responders to anti-interleukin (IL)-5 (mepolizumab and reslizumab) and anti-IL-5 receptor α (benralizumab) therapies. This stud...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research
In patients with eczema that is difficult to manage, it is important to consider the possibility that they are allergic to the topical medications or emollients being used to manage their skin disease. This group of patients may have allergic contact dermatitis (ACD) to topical corticosteroids (TCS), antibiotics, or the excipients and preservatives used in their topical medications or emollients being used for skin care. For this group of patients, topical corticosteroids or the excipients in their vehicle may actually worsen their underlying disease and are the focus of this article.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
Bronchial epithelial interferon- α/β protein expression was deficient in asthma. Lower epithelial interferon-α/β production was associated with adverse clinical outcomes following rhinovirus infection in vivo. Boosting deficient anti-viral immunity in asthma would likely ameliorate exacerbations.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
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Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: CME Review Source Type: research
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