This Year's Top Eye Stories: Detergent Burns, Solar Retinopathy, and More
(MedPage Today) -- The most viewed articles from JAMA Ophthalmology in 2017
Cooking with avocado oil has many well-known advantages, but the oil can also benefit the skin. Here, we look at the research behind its many healing properties. Learn how avocado oil can soothe burns, reduce dandruff, moisturize the face, and reduce inflammation. We also describe the best ways to apply it to the skin.
SCORTEN, used to predict prognosis in Stevens Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS/TEN overlap, is composed of clinical and laboratory variables during the first 24 hours of admission. Despite appropriate treatment, mortality in TEN remains high. Serum lactate on admission and following resuscitation, a powerful predictor of mortality in patients with thermal burns and sepsis, is not included in SCORTEN. Serum lactate is used to guide treatment in patients with severe burns.
Nowadays there are several diseases leading to partial or total atrophy of the hands, such as Epidermolysis Bullosa (EB), arthritis, osteoarthritis, burns or hand amputations. Patients from these diseases are affected to perform their daily activities which include eating, writing, brushing his teeth or drawing. Overall, these patients have their autonomy highly compromised. Current solutions for people with atrophied hands are very basic, mainly because the avalible options are prosthesis for people who lack a whole hand from the wrist up.
Patients who suffer thermal burn injuries while intoxicated with ethanol (approximately half of all severe injuries) experience more complications, longer hospital stays, and almost twice the mortality than non-intoxicated burn patients. Murine models of intoxicated thermal burn injury have revealed that the injury manifests with an acute pro-inflammatory response and delayed immunosuppression but the mechanisms driving these effects are still unclear. The lipid mediator Platelet-activating factor (PAF) promotes inflammation and immunosuppression in response to skin injury but it has not been characterized in intoxicated thermal burn.
Skin pigmentation is a tightly regulated process that can be modulated via internal and external stimuli. Extrinsically, the skin often is exposed to environmental stimuli and stresses such as solar UV and infrared light, as well as to environmental pollution, all of which are able to modulate skin pigmentation. Post-inflammatory hyperpigmentation (PIH) is a common, acquired pigmentary disorder caused by inflammatory dermatoses (including acne-related hyperpigmentation), infections, reaction to drugs, dermatologic procedures, and external injury (burns, frictions, trauma).
There is not enough evidence available to guide wound care management in patients with Stevens-Johnson Syndrome (SJS)/ Toxic Epidermal Necrolysis (TEN). Current guidelines are based on expert opinion and mimic burn wound treatments, including the use of silver-impregnated dressings. Silver-containing dressings reduce the risk of invasive infection by minimizing the bacterial colonization of wounds. Evidence from small clinical trials in burn patients and a retrospective study in SJS/TEN patients indicate that they offer the advantage of not requiring daily dressing changes, which may damage the healing epidermis, and minim...
Cysteinyl leukotrienes (CysLTs; LTC4, LTD4, and LTE4) are inflammatory mediators known for their involvement in bronchoconstriction, asthma and allergy, and primarily signal through the receptors CysLT1 and CysLT2. Interestingly, recent studies have found that CysLT receptors are expressed in normal skin, and that CysLT signaling may interfere with wound healing. Furthermore, our preliminary data show that enzymes associated with CysLT synthesis are highly upregulated in burned murine skin compared to healthy skin, while a previous study showed that blister fluids from burn patients contain high LTC4 levels.
In this study we used a porcine burn wound model to explore the expression and functions of laminins and some important dermal matrix proteins and regulators in wound repair. Swine were used for our animal model since their skin is morphologically similar to human skin.
(Natural News) Elephants aren’t known for eating burned wood then breathing out smoke. Yet that’s exactly what conservation scientists at India’s Nagarahole National Park came across while checking out hidden camera traps. In the 57-second video, a female Asian elephant can be seen scooping up chunks of ashen wood with her trunk and stuffing them...
This study analyses the epidemiological characteristics of bus fires in mainland China over the past 10 years to develop prevention strategies and emergency procedures for such incidence and the resulting casualties. METHODS: We collecte...