CT Scans Reduce Lung Cancer Deaths ... But Among Whom?

(MedPage Today) -- Question of best population to screen remains contentious
Source: MedPage Today Public Health - Category: American Health Source Type: news

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BackgroundThe study was conducted to evaluate the performance of a state ‐of‐the‐art commercial deep learning‐based computer‐aided diagnosis (DL‐CAD) system for detecting and characterizing pulmonary nodules.MethodsPulmonary nodules in 346 healthy subjects (male: female  = 221:125, mean age 51 years) from a lung cancer screening program conducted from March to November 2017 were screened using a DL‐CAD system and double reading independently, and their performance in nodule detection and characterization were evaluated. An expert panel combined the results of the DL‐CAD system and doubl...
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Radiation oncologist Dr. Andrea McKee believes deaths from lung cancer — including those related to asbestos exposure — could be reduced significantly by increased utilization of early CT screening. McKee, chair of radiation oncology at Lahey Hospital and Medical Center in Burlington, Maine, has been a strong proponent of early screening for several years. “We could be saving tens of thousands of lives every year with this,” McKee told The Mesothelioma Center at Asbestos.com. “There is nothing else like it. The life-saving potential is the most important thing that has happened to cancer in my...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Accurately detecting and examining lung nodules early is key in diagnosing lung cancers and thus one of the best ways to prevent lung cancer deaths. Radiologists spend countless hours detecting small spherical...
Source: BMC Medical Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
Introduction: Multiple cardiac metastases from nonsmall-cell lung cancer are extremely rare. Multiple cardiac metastases detected by 18F-fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG PET/CT) have not been previously reported. Patient concerns: A 53-year-old man was admitted to the hospital with left back pain for 1 month. Diagnoses: A contrast-enhanced computed tomography (CECT) scan showed a moderately enhancing mass with a necrotic area in the upper left lobe of the lung and a filling defect in the interventricular septum. Two-dimensional transthoracic echocardiography identified a ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Rationale: For metastatic non-small cell lung cancer with no epidermal growth factor receptor mutations or anaplastic lymphoma kinase gene rearrangements, programmed cell death-1 (PD-1) blockade is preferentially recommended post first-line chemotherapy. However, still many patients do not respond to these agents. After development of resistance to PD-1 blockade, further evaluation of chemotherapy regimen will be necessary. Patient concerns: A 57-year old man had cough with minimal whitish expectoration. Computed tomography (CT) scans showed that he had an upper lobe mass of his left lung and multiple lymphadenectasis...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Grand River Hospital in Waterloo, Ontario is introducing a portable multi-energy x-ray imager as an alternative to CT scan for lung cancer screening. The makers of the device claim it to be cost-effective and emit 50 times less radiation than a CT scan.The creators of the x-ray are KA Imaging, a Canada-based startup with a robust and innovative range of medical imaging products. Previously, they were awarded  $1 million Canadian dollarsfrom the Grand Challenges Canada fund to develop a LCD-based x-ray that uses less radiation and is cheaper to manufacture." With our single X-ray, you sort of walk up to the X-ray,...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
CONCLUSIONS: The methodology shows high performance compared with the state-of-the-art results, in terms of accuracy and efficiency, from both existing CNN-based approaches and engineered feature-based classifications. PMID: 30452432 [PubMed - as supplied by publisher]
Source: Journal of X-Ray Science and Technology - Category: Radiology Tags: J Xray Sci Technol Source Type: research
CONCLUSIONS:: The model predicting patient survival following SABR in NSCLC may be useful in future studies by enabling prediction of survival-based outcomes using radiomics features in CT images. ADVANCES IN KNOWLEDGE:: Quantitative image features from NSCLC nodules on CT images have been found to significantly separate patient populations based on overall survival (p = 0.04). In the long term, a non-invasive method to estimate treatment outcomes in patients undergoing SABR would be valuable, especially since access to tissue specimens is often difficult in these cases. PMID: 30457885 [PubMed - as supplied by publisher]
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
Conclusion: An adequate interpretation of follow-up radiologic examinations is crucial not to miss a post-operative complication or even recurrenceDifferentiating recurrence from postsurgical changes could be challenging for radiologists; reviewing evolution of imaging patterns of previous exams may be helpful to distinguish them.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Imaging Source Type: research
This study is managed by the departmental cancer screening agency (ADEMA80).All general practitioners, pulmonologists and radiologists from Somme were solicited by mail to participate in this study.218 general practitioners, 17 pneumologists and 28 radiologists accepted to participate in this study. 998 subjects were recruited in 20 months and 663 scans were performed representing a participation rate of 66%. Screening was negative in 608 cases (92%), positive in 42 (6.3%) and indeterminate in 13 (1.9%).17 cancers were detected. There were 10 adenocarcinomas,2 squamous cell carcinomas, 1 carcinoid tumor, 2 small cell carci...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung Cancer Source Type: research
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