CT Scans Reduce Lung Cancer Deaths ... But Among Whom?

(MedPage Today) -- Question of best population to screen remains contentious
Source: MedPage Today Public Health - Category: American Health Source Type: news

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Authors: Sasaki A, Egashira H, Sugimoto H, Seki K, Tsukiyama T, Ichita C, Tokoro S, Takizawa S, Kitagawa I, Teshima S, Kako M Abstract A 69-year-old male patient presented with multiple lung nodules revealed by chest-computed tomography (CT) during a preoperative examination for an appendiceal tumor. The nodule diameters ranged from 2-10 mm without either pleural thickening or effusions. A fluorine-18-labeled fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET)/CT scan showed a high FDG uptake in the appendiceal tumor, but almost normal standardized uptake values in the bilateral lung nodules. A CT-guide...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
CONCLUSIONS: Acquired hemophilia A is a rare but potentially severe disease, which may be idiopathic or linked to a solid tumor. The severity of AHA depends on both the volume of hemorrhage and the presence of associated diseases. PMID: 30098880 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Phys Med Biol. 2018 Aug 10;: Authors: Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C Abstract Lung cancer mortality rate can be significantly reduced by up to 20% through routine low-dose computed tomography (LDCT) screening, which, however, has high sensitivity but low specificity, resulting in a high rate of false-positive nodules. Combining PET with CT may provide...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
Publication date: Available online 7 August 2018Source: Respiratory Medicine Case ReportsAuthor(s): Noni Novisari Soeroso, Setia Putra Tarigan, Wina Saragih, Novie Diana Sari, Netty Lubis, Humairah LubisAbstractOrbital metastasis of lung adenocarcinoma is very rare. The incidence is only found to be approximately 7%–12% of lung cancer cases. The lack of knowledge about orbital metastasis results in misdiagnosis between malignant or benign lesion. This was a case of a 39-year-old woman complaining about a protruding left eye and a blind pain in the left eye characterized by hyperemesis eyeball. A CT scan of the orbita...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Conclusion: Significantly more patients had unilateral rather than bilateral regional differences (both increases and decreases) in 18F-FDG uptake in the brain pre-and post PCI. This suggests that differences in unilateral distribution are related to functional changes, since direct toxicity alone from PCI and chemotherapy would be symmetric. The frontal region was the most commonly affected, suggesting a potential contributing etiology for cognitive impairment and decreased executive function after therapy. PMID: 30076247 [PubMed - as supplied by publisher]
Source: Journal of Nuclear Medicine Technology - Category: Nuclear Medicine Tags: J Nucl Med Technol Source Type: research
While lung cancer isn ’t the most common cancer in New Zealand, it is the most deadly cancer, accounting for almost 20% of all cancer deaths in New Zealand [1]. Lung cancer carries a high mortality because it is usually detected at a late stage, when the disease is advanced, spread to other parts of the body, with low survival. There is growing evidence that screening current and ex-smokers for lung cancer with low-dose computed tomography (LDCT) scans is effective at reducing lung cancer mortality.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
Publication date: Available online 1 August 2018Source: European Journal of RadiologyAuthor(s): Kisoo Pahk, Jae Ho Chung, Eunjue Yi, Sungeun Kim, Sung Ho LeeABSTRACTObjectivesAccurate prediction of pathological N2 metastasis is crucial for choosing the best therapeutic strategy for non-small cell lung cancer (NSCLC) patients. The aim of this study is to evaluate the usefulness of metabolic heterogeneity assessed by the positron emission tomography combined with computed tomography (PET/CT) using F-18 fluorodeoxyglucose (FDG) in primary NSCLC with clinically suspected N2 metastasis in predicting pathological mediastinal lym...
Source: European Journal of Radiology - Category: Radiology Source Type: research
We report a case of a patient diagnosed with locally advanced non-small cell lung cancer. Interventions: The patient declined potentially curative treatment, and did not receive any anti-cancer treatment. Outcomes: He has survived more than two years since his initial diagnosis, maintaining his good performance status. Serial imaging with computed tomography scans showed tumour regression and near-complete resolution of his disease. Lessons: Spontaneous regression of non-small cell lung cancer, by virtue of its scarcity, has not been well-studied and is poorly understood. Further studies are required, in order to ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
The aim of this study was to evaluate the relationship between maximum standardized uptake value (SUVmax) with tumor size and tumor pathological characteristics as well as suggesting equations between SUVmax and tumor size in patients with nonsmall cell lung cancer (NSCLC) to help differentiate between pathology types. We retrospectively analyzed the fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) findings of 98 patients with NSCLC. Statistical differences were considered significant when P 
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
ConclusionsTime-courses of whole tumor FMISO uptake by advanced stage NSCLC are described best by an irreversible three-tissue compartment model. TheK1 values obtained from fits of the irreversible three-tissue model correlated strongly with independent blood flow measurements obtained from perfusion CT (r = 0.81).
Source: EJNMMI Research - Category: Radiology Source Type: research
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