Is 300 Seconds ACT Safe and Efficient during MiECC Procedures?

CONCLUSION:  Since no evidence of increased thrombin formation (ETP) was found from a laboratory standpoint, we concluded that the use of MiECC with a reduced anticoagulation strategy seems possible. This alternative anticoagulation strategy leads to significant reduction in dosages of both heparin and protamine. We can confidently move forward with investigating this anticoagulation concept. However, to establish clinical safety of ACT below 300 seconds, we need larger clinical studies.
PMID: 29290078 [PubMed - as supplied by publisher]

Source: The Thoracic and Cardiovascular Surgeon - December 31, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Bauer A, Hausmann H, Schaarschmidt J, Szlapka M, Scharpenberg M, Eberle T, Hasenkam JM Tags: Thorac Cardiovasc Surg Source Type: research