Bayesian analysis improves pulse secretion characterization in reproductive hormones.
In conclusion, Bayesian analysis provides a more reliable pulse characterization in low signal-to-noise experiments and should be used for the analysis of reproductive physiology studies of pulsatile hormones. Software is available at www.github.com/BayesPulse .
ABBREVIATIONS: LH: luteinizing hormone; FSH: follicle stimulating hormone; GnRH: gonadotropin-releasing hormone; FP: false positive; FN: false negative.
PMID: 29287490 [PubMed - as supplied by publisher]
Source: Systems Biology in Reproductive Medicine - Category: Reproduction Medicine Authors: Liu H, Polotsky AJ, Grunwald GK, Carlson NE Tags: Syst Biol Reprod Med Source Type: research