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Does hormone replacement therapy promote better quality of sleep in women? Results from a large cross-sectional norwegian study (Hunt 3)

Introduction: Hormone replacement therapy (HRT) is commonly prescribed to alleviate some of the symptoms of the menopause, which often are associated with higher frequency of sleep problems (Ameratunga, Goldin,&Hickey, 2012). The effect of use of HRT on sleep quality is, however, controversial. Therefore, the aim of this study was to investigate possible associations between HRT and good quality sleep in Norwegian women. Other factors, as satisfaction with life, neuroticism, frequency of night sweats and selected life style factors as smoking, frequency of exercise, and marital status (co-habiting or not) were also investigated.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Pharmacology Source Type: research

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BOSTON (CBS) — Scientists at Imperial College London have developed a new class of experimental drugs to treat menopausal hot flashes. In a clinical trial involving 37 women, the compound called MLE4901 reduced the number of hot flashes by almost three-quarters and significantly reduced the severity. The drug blocks a chemical in the brain called neurokinin B and in the study the drug also improved sleep and concentration during the 4-week study period. MLE4901 can affect liver function but two similar drugs which don’t have this side effect are being studied in larger patient trials including one in the U.S. t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Healthwatch Local News Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall Menopause Women's Health Source Type: news
Breast cancer is the most frequent cancer among women especially in the Western world where, despite improved survival, it is one of the leading causes of death (1). Furthermore, for several decades there has been an increase in incidence, though recently there seems to be a stabilization in risk or even a small decline in typical high-risk areas such as Europe and the USA but at the same time a steep increase in typical low-risk societies such as Japan (2). Breast cancer is often regarded as a singular disease, but recent discoveries are pointing to a variety of types of potentially different etiology. Thus, the female...
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Tags: Editorial Source Type: research
It’s not going to kill you to take hormone replacement therapy. That’s the take home message from the latest analysis of the Women’s Health Initiative, the largest and longest randomized trial of hormone replacement therapy (HRT) in menopausal women. After almost 18 years of follow up in the WHI, there was no increase in overall mortality, including death rates from cancer, in women taking HRT for up to 5.6 years (estrogen plus progestin) or 7.2 years (estrogen alone). There was a non-significant reduction in mortality among those who started HRT between ages 50 and 59, the group most likely to ...
Source: The Blog That Ate Manhattan - Category: Primary Care Authors: Tags: Hormone Replacement Menopause WHI breast cancer estrogen HRT Prempro Source Type: blogs
Abstract Menopause is for many females associated with an occurrence of a variety of health complaints and a decrease in quality in life. Hot flashes, sleep disturbances and a variety of other symptoms result in a strong psychological strain. Hormone replacement therapy for treatment of climacteric complaints is discussed controversially regarding associated side effects. This is a major reason to propose treatment with plant derived extracts and compounds as an alternative. Such compounds are available either as drugs but mostly as nutritional supplements. Here we have to distinguish betw...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - Category: Global & Universal Authors: Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research
Image Source Who doesn't want to enjoy the whole life offered by God with full zest? However, it is only possible when one is at his best health. As the age increases, the body starts experiencing various kinds of hormonal changes which interfere with the normal functioning of the body as well as leading to diseases many a times. Some of the common problem faced by people due to hormonal misbalance includes weight gain, memory decline, fatigue, low libido, and aging appearance and muscle loss. With advancements in the field of medical science, now you don't need to bother anymore about these problems. Yes, it is curable n...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Some women can experience up to 30 hot flushes in a 24-hour period, seriously disrupting their sleep, relationships and work
Source: Telegraph Health - Category: Consumer Health News Tags: menopause hot flushes Imperial College London hormone replacement therapy HRT Source Type: news
Abstract Purpose Obstructive sleep apnea syndrome (OSAS) has a higher prevalence in postmenopausal women who are not on hormone replacement therapy (HRT), as compared to premenopausal women. Cognitive impairment (CI) is associated with OSAS and the early postmenopausal state. We hypothesized that compared to postmenopausal women at low risk for OSAS, postmenopausal women at high risk for OSAS would report worse cognitive function. Methods Early postmenopausal women not on HRT between the ages of 45 and 60 years, within 5 years of natural menopa...
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
Abstract PURPOSE: Obstructive sleep apnea syndrome (OSAS) has a higher prevalence in postmenopausal women who are not on hormone replacement therapy (HRT), as compared to premenopausal women. Cognitive impairment (CI) is associated with OSAS and the early postmenopausal state. We hypothesized that compared to postmenopausal women at low risk for OSAS, postmenopausal women at high risk for OSAS would report worse cognitive function. METHODS: Early postmenopausal women not on HRT between the ages of 45 and 60 years, within 5 years of natural menopause, were enrolled. Participants completed a REDCap su...
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
Abstract Purpose Obstructive sleep apnea syndrome (OSAS) has a higher prevalence in postmenopausal women who are not on hormone replacement therapy (HRT), as compared to premenopausal women. Cognitive impairment (CI) is associated with OSAS and the early postmenopausal state. We hypothesized that compared to postmenopausal women at low risk for OSAS, postmenopausal women at high risk for OSAS would report worse cognitive function. Methods Early postmenopausal women not on HRT between the ages of 45 and 60 years, within 5 years of natural menopa...
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
As we age, one of the first things to go is often our hormone balance. Hormones are the critical chemicals that keep our bodies in alignment, help us get enough sleep and maintain our energy levels. As we get older our hormone levels change. Throw in the stress that many of us feel from raising children, managing careers, taking care of ill or aging parents, and the result? Low energy and an overall feeling of exhaustion! Lori Van Popering, a Certified Holistic Practitioner and Coach, has been there! She knows what it’s like to feel exhausted, foggy and just “not herself”. Her hot flashes, weight gain, di...
Source: Disruptive Women in Health Care - Category: Consumer Health News Authors: Tags: Consumer Health Care Source Type: blogs
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