Effects of sleep architecture and sleep apnea on Alzheimer's disease biomarkers in cognitively normal elderly

Introduction: Increasing evidence suggests sleep can influence the risk for development of Alzheimer disease (AD), but the precise features of sleep architecture influencing this risk and the role of obstructive sleep apnea (OSA) in contributing to this risk remain only partially characterized. Current models of AD suggest that pathological changes, including the accumulation of proteins beta-amyloid (A β) and tau, can occur years to even decades before clinical symptoms of memory impairment become evident.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Aging and Developmental Issues Source Type: research