Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta.

Conclusions: We successfully generated iPSCs and iPSC-NSPCs from surgical samples obtained from newborns with SBa with the goal of future clinical use in patients with SBa. PMID: 29279741 [PubMed]
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research

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Purpose of review The aim of this article is to give an overview of recent literature on transitional care of children with complex urological disease. Recent findings Most studies on transitional care concerned spina bifida patients. Assessment of current practices revealed that formalized clinics for transitional care may improve healthcare. However, there is still little consensus among healthcare providers on how to organize transitional care. A widely recognized problem is a lack of interested, dedicated, and well-trained staff for transitional care and lifelong follow-up of complex urological patients and also a...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: NEUROUROLOGY AND INCONTINENCE: Edited by John Heesakkers and Frank Martens Source Type: research
Publication date: July 2020Source: Research in Developmental Disabilities, Volume 102Author(s): Lucie Attout, Marie-Pascale Noël, Laurence Rousselle
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
AbstractAimTo compare the quality of life (QoL) in children with spina bifida with a control group of their peers using a validated questionnaire, the Neurogenic Bowel Dysfunction Score (NBDS).MethodsThe NBDS questionnaire was prospectively distributed to children attending a multi-disciplinary Spina Bifida clinic and healthy controls attending pediatric urology clinics. A score (out of 41) was assigned to each child based on their responses to the validated questionnaire. A lower score indicates better bowel function-related quality of life. SPSS software (v.25) was used for all statistical analysis.ResultsThere were 98 r...
Source: Pediatric Surgery International - Category: Surgery Source Type: research
Publication date: Available online 11 May 2020Source: International Journal of Surgery Case ReportsAuthor(s): Lionel El Khoury, Rosa Benvenga, Joel Roussel, Rodolfo Romero, Regis Cohen, Nassir Habib, Jean-Marc Catheline
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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Source: Pediatric Hematology and Oncology - Category: Pediatrics Authors: Source Type: research
Conditions:   Neural Tube Defects;   Spina Bifida;   Myelomeningocele Interventions:   Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique;   Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique Sponsor:   University of Southern California Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Open Spina Bifida;   Myelomeningocele;   Meningomyelocele;   Chiari Malformation With Spina Bifida;   Chiari Malformation Type 2 Intervention:   Other: Neuropsicomotor developmental test Sponsor:   Hospital Israelita Albert Einstein Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 15 May 2017 Source:Stem Cell Research Author(s): Mario Marotta, Alejandra Fernández-Martín, Marc Oria, Cesar G. Fontecha, Carles Giné, Vicente Martínez-Ibáñez, Elena Carreras, Michael A. Belfort, Gloria Pelizzo, Jose L. Peiró Despite benefits of prenatal in utero repair of myelomeningocele, a severe type of spina bifida aperta, many of these patients will still suffer mild to severe impairment. One potential source of stem cells for new regenerative medicine-based therapeutic approaches for spinal cord injury repair is neural progenitor ce...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
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