Surveillance of Antimicrobial Susceptibilities of Neisseria gonorrhoeae from 2013 to 2015 in Guangxi Province, China.

Surveillance of Antimicrobial Susceptibilities of Neisseria gonorrhoeae from 2013 to 2015 in Guangxi Province, China. Jpn J Infect Dis. 2017 Dec 26;: Authors: Li W, Zhu BY, Qin SQ, Yang MC, Liang M, He S, Chen HZ, Gan Q, Huang YJ, Wei JP, He JZ, Chen Z, Bu J Abstract Neisseria gonorrhoeae (N. gonorrhoeae) is a sexually transmitted pathogen popular worldwide with increased trend of resistance to antimicrobial treatment. We conducted this study to trace the antimicrobial susceptibilities of N. gonorrhoeae to penicillin, spectinomycin, ciprofloxacin, azithromycin, cefixime and ceftriaxone in Guangxi. Totally 303 NG isolates were sampled from patients infected with N. gonorrhoeae from five cities in Guangxi 2013-2015, and the antibiotic susceptibilities were tested by Agar dilution assay. The results showed that N. gonorrhoeae was susceptible to cephalosporins treatment including ceftriaxone (99.7%), cefixime (99%), spectinomycin (100%), and azithromycin (96.4%), and it was the first report of antibiotic susceptibilities for azithromycin surveillance to N. gonorrhoeae in Guangxi. PPNG with percentage rose from 37% in 2013 to 64% in 2015 (P=0.068), and TRNG rate increased from 23% in 2013 to 44% in 2015 (P = 0.071). High resistance of N. gonorrhoeae to penicillin was associated with infection age of 25 to 30 years (P<0.05) and PPNG positive (P<0.01), and TRNG positive was risk factor for ciprofloxacin resistance (P=0.0407). Our stud...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research