Multiple roles of silver salts in palladium-catalyzed C –H activations

Publication date: Available online 27 December 2017 Source:Journal of Organometallic Chemistry Author(s): Katherine L. Bay, Yun-Fang Yang, K.N. Houk Many Pd-catalyzed C–H functionalization reactions utilize stoichiometric Ag(I)-salts as additives. Ag additives are typically used either as a terminal oxidant or as a halide scavenger for Pd catalyst regeneration. However, recent experimental and computational studies have shown that Ag(I)-salts may play additional roles in C–H activation processes. Notably, cooperative Pd–Ag bimetallic C–H activations and Ag(I)-mediated Pd-catalyzed C–H arylations can occur. The non-oxidative roles of Ag(I) salts in Pd-catalyzed C-H activation are highlighted in this mini-review. Graphical abstract

Source: Journal of Organometallic Chemistry - December 28, 2017 Category: Chemistry Source Type: research