Study: Legacy pacers, ICDs found safe for 1.5T MRI scans

Pacemakers and implantable cardioverter defibrillators not marked as MRI-safe could still be mostly safe to use during imaging sessions with 1.5T MRI machines, according to a new study reported on by Healio. Results from the study were recently published in The New England Journal of Medicine. In the prospective, nonrandomized study, researchers aimed to explore the safety of 1.5T MRI sessions in 1,509 patients with legacy pacemakers or ICDs, undergoing a total of 2,103 MRI exams. Pacing mode in the devices was changed to asynchronies in pacing dependent patients and demand mode for other patients, with tachyarrhythmia functions disabled, according to Healio. No clinically significant adverse events were reported at 1 year, according to the report, and only 0.4% of the devices reset to backup mode during MRI exams. A single pacer with a month of battery life was noted as having reset to ventricular inhibited pacing, could not be reprogrammed and was replaced, according to the report. A decrease P-wave amplitude of at least 50% from baseline also occurred in 1% of patients, according to Healio. On a longer term follow-up, 4% of patients had reported decreases in P-wave amplitude, with 4% experiencing an increase in atrial capture threshold, 4% exhibiting an increase in right ventricular capture threshold and 3% showing an increase in left ventricular capture threshold, according to the report. None of these results were clinically significant or required device reprogramming o...
Source: Mass Device - Category: Medical Devices Authors: Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Clinical Trials Imaging Source Type: news

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ander Studded tires are used in a number of countries during winter in order to prevent accidents. The use of tire studs is controversial and debated because of human health impacts from increased road particle emissions. The aims of this study are to assess whether the use of tire studs in a Scandinavian studded passenger car actually avoids or causes health impacts from a broader life cycle perspective, and to assess the distribution of these impacts over the life cycle. Life cycle assessment is applied and the disability-adjusted life years indicator is used to quantify the following five types of health impacts: (1...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionNo difference in postural venous outflow between patients with MS and healthy controls was found. However, when the abnormal ΔCVF is present within the MS population, it may be associated with more inflammatory and neurodegenerative pathology. Further studies should explore whether the orthostatic venous changes are an aging or an MS-related phenomenon and if the etiology is due to impaired autonomic nervous system funct ioning.
Source: Clinical Autonomic Research - Category: Research Source Type: research
Conclusion and ImplicationsComparisons of bone measures with Australian comparative data are similar to European findings however sex differences were found in the present study. Australian adolescent boys with LMC/DCD had less robust bones compared to their well-coordinated Australian peers, whereas there were no differences between groups for girls. These differences may be due to lower levels of habitual weight–bearing physical activity, which may be more distinct in adolescent boys with LMC/DCD compared to girls.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
adapted from Figure 3 (Koroshetz et al., 2018). Magnetic resonance angiography highlighting the vasculature in the human brain in high resolution, without the use of any contrast agent, on a 7T MRI scanner. Courtesy of Plimeni&Wald (MGH).[ed. note: here's a great summary onIf, how, and when fMRI goes clinical, by Dr. Peter Bandettini.]TheJournal of Neuroscience recently published a paywalled article onThe State of the NIH BRAIN Initiative.This paper reviewed the research and technology development funded by the “moonshot between our ears” [anewly coined phrase]. The program has yielded a raft ofpublications...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs
Conclusions:PI and FBI showed a significant correlation with both ODI and SRS-22 scores. PI-LL mismatch was strongly correlated with disability in high PI patients. Our study results may indicate that it is important to pay attention to the PI value in addition to the spinopelvic relationship.Level of Evidence: II, prospective study
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
Publication date: Available online 10 August 2018Source: NeuroImage: ClinicalAuthor(s): Pedro M. Paz-Alonso, Myriam Oliver, Garikoitz Lerma-Usabiaga, Cesar Caballero-Gaudes, Ileana Quiñones, Paz Suárez-Coalla, Jon Andoni Duñabeitia, Fernando Cuetos, Manuel CarreirasAbstractDevelopmental dyslexia is one of the most prevalent learning disabilities, thought to be associated with dysfunction in the neural systems underlying typical reading acquisition. Neuroimaging research has shown that readers with dyslexia exhibit regional hypoactivation in left hemisphere reading nodes, relative to control counterpart...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Acta Neurologica Scandinavica,Volume 0, Issue ja, -Not available-.
Source: Acta Neurologica Scandinavica - Category: Neurology Authors: Source Type: research
According to Wiktionary, a guideline is a plan to guide one in setting standards or determining a course of action. In occupational safety and health (OSH), there are two basic problems for which guidance can be helpful. The first is under which circumstances or exposures a worker is at risk of adverse health effects. The second is which actions can be taken to ensure that a worker is safe from these risks. For both problems, one would like to see solid evidence: first that there is a risk and then that interventions can keep workers safe. Very similar problems exist in environmental health, nutrition and water safety. W...
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Tags: Editorial Source Type: research
AbstractStroke at the acute stage is a major cause of disability in adults, and is associated with dysfunction of brain networks. However, the mechanisms underlying changes in brain connectivity in stroke are far from fully elucidated. In the present study, we investigated brain metabolism and metabolic connectivity in a rat ischemic stroke model of middle cerebral artery occlusion (MCAO) at the acute stage using18F-fluorodeoxyglucose positron emission tomography. Voxel-wise analysis showed decreased metabolism mainly in the ipsilesional hemisphere, and increased metabolism mainly in the contralesional cerebellum. We used ...
Source: Neuroscience Bulletin - Category: Neuroscience Source Type: research
In this study, we analyzed FGF21 levels and alterations in the expression of genes encoding components of the FGF21-responsive molecular machinery in adipose tissue from aged individuals so as to ascertain whether altered FGF21 responsiveness that develops with aging jeopardizes human health and/or accelerates metabolic disturbances associated with aging. We studied a cohort of 28 healthy elderly individuals (≥70 years) with no overt signs of metabolic or other pathologies and compared them with a cohort of 35 young healthy controls (≤40 years). Serum FGF21 levels were significantly increased in elderly indiv...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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