Randomised, double-blind, controlled clinical trial on the antiseptic efficacy by reduction of CFU with polihexanide 0.04% on acute traumatic wounds
Publication date: Available online 28 December 2017 Source:Journal of Hospital Infection Author(s): Barbara Payne, Hans-Peter Simmen, Esther Csuka, Matthias Hintzpeter, Steffen Pahl, Florian H.H. Brill Prevention of wound infections is a challenge in clinical practice. The aim of this study was to assess the efficacy of polihexanide 0.04 % on acute traumatic wounds. It was a randomised, double-blind, placebo-controlled prospective trial which included 61 patients. The polihexanide group showed a significant decrease in log10 CFU (p<0.001) after 60 min treatment in comparison to baseline CFU, whereas the Ringer’s solution group did not show a significant change of CFU during 60 min treatment. Treatment of polihexanide 0.04% resulted in a significant reduction of bacterial load in acute traumatic wounds.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research