Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study
Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE studySerum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study, Published online: 27 December 2017; doi:10.1038/s41391-017-0030-9Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study
The study couldn't prove cause and effect, but it found that statins, taken alone or with metformin, did seem associated with an increase in survival.
FRIDAY, Feb. 14, 2020 -- Drugs that many men with prostate cancer might already be taking -- cholesterol-lowering statins -- may help extend their survival if they have a " high-risk " form of the disease, new research suggests. High-risk patients...
Title: Cholesterol Drugs Might Help Curb 'High-Risk' Prostate CancersCategory: Health NewsCreated: 2/14/2020 12:00:00 AMLast Editorial Review: 2/14/2020 12:00:00 AM
ConclusionsStatin use alone or in combination with metformin was associated with lower all ‐cause and PCa mortality among high‐risk patients, particularly in post‐diagnostic settings; further studies are warranted.
(Thomas Jefferson University) Statin use alone or with metformin is associated with lower prostate cancer mortality from all causes, among high-risk patients.
Prostate Cancer and Prostatic Diseases, Published online: 06 February 2020; doi:10.1038/s41391-020-0207-5Associations among statins, preventive care, and prostate cancer mortality
Androgen receptor targeted therapies have emerged as an effective tool to manage advanced prostate cancer (PCa). Nevertheless, frequent occurrence of therapy resistance represents a major challenge in the clin...
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ConclusionMetformin and statins were not associated with BFFS or DFFS improvement in our analysis. However, the small number of patients treated with these drugs limits the reliability of the results and prospective studies are needed.