The effects of concurrent chemoradiation therapy to the base of tongue in a preclinical model

ConclusionsThe current study is the first to describe a preclinical model of CCRT to the head and neck with an emphasis on clinical relevance. Tongue strength decreased at 2 weeks and 5 months post‐CCRT. Tongue displacement increased only at 5 months post‐CCRT. Fibrosis was not detected, implicating alternative causative factors for these findings.
Level of EvidenceNA Laryngoscope, 2017

Source: The Laryngoscope - December 27, 2017 Category: ENT & OMF Authors: Peter A. Benedict, Ryan Ruiz, Avanti Verma, Gregory R. Dion, Philmo Oh, Binhuan Wang, Omar H. Ahmed, Nao Hiwatashi, Renjie Bing, Kristen Victor, Kenneth S. Hu, Aaron Johnson, Ryan C. Branski, Milan R. Amin Tags: Original Reports Source Type: research