Low-Normal Thyroid Implicated in Unexplained Infertility Low-Normal Thyroid Implicated in Unexplained Infertility

Thyroid hormone levels at the low end of normal are twice as common in women with unexplained infertility as those with normal fertility, hinting at a possible role for thyroid hormone replacement.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

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Publication date: Available online 15 August 2018Source: SteroidsAuthor(s): Julius Fink, Masahito Matsumoto, Yoshifumi TamuraAbstractSedentary lifestyle and over-nutrition are the main causes of obesity and type 2 diabetes (T2D). However, the same causes are major triggers of hypogonadism. Many T2D patients show low testosterone levels while hypogonadal men seem to be prone to become diabetic. Testosterone plays a major role in the regulation of muscle mass, adipose tissue, inflammation and insulin sensitivity and is therefore indirectly regulating several metabolic pathways, while T2D is commonly triggered by insulin resi...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Abstract Polycystic ovary syndrome (PCOS) usually arises during puberty and is marked by insulin resistance, hyperinsulinemia, and hyperandrogenism. The principle is that the diagnosis of PCOS must be based on the presence of at least two of the following three criteria: chronic anovulation, hyperandrogenism (clinical or biological), and polycystic ovaries. The diagnosis of PCOS in adolescents is particularly difficult due to developmental problems in this group. Many symptoms of PCOS, including acne, menstrual irregularities, and hyperinsulinemia, are common in normal puberty. Adolescents with PCOS are at an incr...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - Category: Endocrinology Authors: Tags: Pediatr Endocrinol Diabetes Metab Source Type: research
(CNN) — Alzheimer’s disease. Diabetes. Arthritis. Unwanted hair growth. Baldness. Infertility. Erectile dysfunction. Hangovers. Glaucoma. Cancer. If you have an ailment, there’s a good chance that someone, somewhere, is studying whether turmeric can treat it. There are more than 15,000 manuscripts published about curcumin, the active ingredient in turmeric, and about 50 manuscripts added to this collection each week, according to the National Institutes of Health. “It’s really taken on sort of panacea-like properties in terms of the things it’s being studied for and the things it has bee...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local TV turmeric Source Type: news
Abstract Context: Women with PCOS are at increased risk for pregnancy complications possibly related to pre-existing obesity and potentially to excessive gestational weight gain (GWG). Objectives: To assess the contributions of pre-existing diagnosis and preconception weight on GWG and perinatal outcomes. Research Design and Methods: Prospective cohort study of singleton pregnancies in PCOS(N =164) and ovulatory controls(N = 176) conceiving from infertility treatment. Main Outcome measures: GWG, birthweight, pregnancy complications. Results: From pre-conception baseline, normal-weight PCOS women gai...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
AbstractTesticular apoptotic cell death (TACD) contributes to diabetes  mellitus (DM)-induced male infertility. MicroRNA-34a (miR-34a) is a pro-apoptotic RNA that targets sirtuin 1 (SIRT1) which provides protection against complications of (DM). However, the specific role of miR-34a in (DM)-induced TACD is unknown. MiR-34a targetsSirt1 mRNA, resulting in apoptosis. However, whether or not SIRT1 is a major target of miR-34a in (DM)-induced TACD is unclear. The present study aimed to define the role of miR-34a/SIRT1 in (DM)-induced TACD. C57BL/6 male mice were induced to (DM) by streptozotocin, for a period of 24  ...
Source: Journal of Molecular Medicine - Category: Molecular Biology Source Type: research
ConclusionFindings of this study showed that risk factors of recurrent abortion, TPO-Ab and uterine leiomyoma have significant importance in pregnant patients undergoing ART.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
Publication date: July 2018Source: The Lancet Diabetes &Endocrinology, Volume 6, Issue 7Author(s): Simone De Leo, Elizabeth N PearceSummaryUnderstanding of changes in thyroid function and the consequences of thyroid disease during pregnancy has rapidly grown in the past two decades, and revised American Thyroid Association guidelines on this topic were published in 2017. This Review explores the association between thyroid autoimmunity and complications during and after pregnancy. Thyroid autoimmunity refers to the presence of antibodies to thyroperoxidase or thyroglobulin, or thyroid-stimulating hormone receptor antib...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Publication date: May 2018Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 12, Issue 3Author(s): Muhammad Bilal, Abdul Haseeb, Abdur RehmanAbstractBackgroundPolycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age. The two main documented pathogenic mechanisms are hyperinsulinemia and hyperandrogenemia but there is growing evidence for increased predisposition to cardiovascular disease, dyslipidemia, and type 2 diabetes mellitus. Our study aims to analyze the association of PCOS with cardiovascular risk factors.MethodsThis is a prospective st...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
The objective of the present survey is to list the major plants used in Congolese traditional folk medicine for the treatment of oxidative stress-related diseases as well as to review the phytogeographical distribution of these plants, their natural habitats, plant parts used, routes of administration, and administered doses. Several methods have been used to fulfil the aim of the study: an ethnobotanical survey, observation of the practices of traditional healers, and bibliographical research focused on the ethnobotany and antioxidant power of sub-Saharan African medicinal plants. From a questionnaire, a guided semi-struc...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
ConclusionFindings of this study showed that risk factors of recurrent abortion, TPO-Ab and uterine leiomyoma have significant importance in pregnant patients undergoing ART.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
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