Ketamine induces neuronal apoptosis and cognitive disorder via miR-199a-5p/HIF-1 α in neonatal rats

In conclusion, we suggest that ketamine-induced neuronal apoptosis in neonatal rats, followed by lea rning and memory impairment, might be mediated via the miR-199a-5p/HIF-1α signalling pathway.

http://link.springer.com/10.1007/s13273-017-0044-3

Source: Molecular and Cellular Toxicology - December 1, 2017 Category: Cytology Source Type: research