Neglected vector-borne zoonoses in Europe: into the wild

We present case studies on the role of rodents in the cycles of Bartonella spp., of wild ungulates in the cycle of Babesia spp., and of various wildlife species in the life cycle of Leishmania infantum, Anaplasma phagocytophilum and Rickettsia spp. These examples highlight the usefulness of surveillance strategies focused on neglected zoonotic agents in wildlife as a source of valuable information for health professionals, nature managers and (local) decision-makers. These benefits could be further enhanced by increased collaboration between researchers and stakeholders across Europe and a more harmonised and coordinated approach for data collection.
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research

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ConclusionThe results of this investigation demonstrate for the first time the chemical composition of the hydroethanolic extract of the Ximenia Americana stem bark, your potential antiparasitic and modulatory effect. The low cytotoxic and biological potential against S. aureus open therapeutic perspectives against leishmaniosis and bacterial infections.
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Lucy Evans, 20, was diagnosed with the brain-inflammation condition encephalitis six weeks after her delusions started and treated at Morriston Hospital in Cwmrhydyceirw, Swansea.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
We present the first case of autochthonous VL mimicking SLE in Santa Catarina in southern Brazil.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSIONS: This study shows low circulation of antibodies to R. rickettsii in CVL-seropositive dogs. It is recommended that surveillance studies in dogs should continue in order to monitor this scenario.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Publication date: Available online 20 February 2019Source: Veterinary MicrobiologyAuthor(s): C.A Oliveira Júnior, R.O.S Silva, A.P Lage, F.M Coura, C.P Ramos, A.A. Alfieri, R.M.C Guedes, F.C.F LobatoAbstractNeonatal porcine diarrhea (NPD) is a current problem on pig farms and is caused by several enteropathogens. Among them, Clostridioides difficile stands out due to its importance in piglets and zoonotic potential. A non-toxigenic strain of C. difficile (NTCD), named Z31, was previously tested in hamster and piglet experimental models as a strategy to prevent C. difficile infection (CDI). To evaluate the capacity o...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Lucy Evans had encephalitis, an inflammation of the brain that caused her frightening delusions.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
ConclusionIn silico and docking results were in accordance with the in vitro activity of these compounds in the present study, and EGCG and ECG showed reasonable levels of selectivity for Leishmania.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
We examined the transmission of SNV between deer mice and found that direct contact between deer mice is the main driver of SNV transmission rather than exposure to contaminated excreta/secreta, which is thought to be the main driver of transmission of the virus to humans. Furthermore, increases in heat shock responses or testosterone levels in SNV-infected deer mice do not increase the replication, shedding, or rate of transmission. Here, we have demonstrated a model for the transmission of SNV between deer mice, the natural rodent reservoir for the virus. The use of this model will have important implications for further...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Publication date: Available online 20 February 2019Source: Parasitology InternationalAuthor(s): Nathalia Martinez-Sotillo, Andrea Pinto-Martínez, Elżbieta Hejchman, Gustavo BenaimAbstractLeishmaniasis is a parasitic disease representing an important problem of public health. Visceral leishmaniasis, resulting from infection with Leishmania donovani, causes considerable mortality and morbidity in the poorest region of the word. At present there is no current effective treatment, since the approved, drugs are expensive and are not free of undesirable side effects. Therefore, there is a need for the identification of n...
Source: Parasitology International - Category: Parasitology Source Type: research
Publication date: Available online 19 February 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Ana M. Palomar, Shonnette Premchand-Branker, Pilar Alberdi, Oxana A. Belova, Anna Moniuszko-Malinowska, Olaf Kahl, Lesley Bell-SakyiAbstractTicks harbour and, in many cases transmit to their vertebrate hosts, a wide variety of pathogenic, apathogenic and endosymbiotic microorganisms. Recent molecular analyses have greatly increased the range of bacterial species potentially associated with ticks, but in most cases cannot distinguish between surface contaminants, microorganisms present in the remains of the previous blood meal...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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