Enriched physical environment reverses spatial cognitive impairment of socially isolated APPswe/PS1dE9 transgenic mice before amyloidosis onset.

CONCLUSION: These results suggest that the enriched physical environment may serve as a nonpharmacological intervention for delaying the onset of AD accompanied with social isolation.
PMID: 29274291 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - December 23, 2017 Category: Neuroscience Authors: Cao M, Hu PP, Zhang YL, Yan YX, Shields CB, Zhang YP, Hu G, Xiao M Tags: CNS Neurosci Ther Source Type: research