Pseudomonas aeruginosa control in healthcare settings: outpatient dialysis units are not augmented care units

Publication date: January 2018 Source:Journal of Hospital Infection, Volume 98, Issue 1 Author(s): R. Montgomery, T. Boswell, N. Mahida
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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Abstract In the future, stem cell-based technologies may be harnessed to replace conventional dialysis and transplantation in patients with diabetic nephropathy. Recently, there has been considerable effort to improve methods for the differentiation of human pluripotent stem cells (hPSCs) into kidney cells in culture. Here, we present a protocol for obtaining more advanced kidney structures than have currently been possible in vitro, including vascularized glomeruli and tubular elements. HPSCs are first differentiated in 2D culture to a kidney progenitor stage. These cells are then dissociated and injected subcuta...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
Abstract Extracellular vesicles are lipid bilayer enclosed structures secreted by all cell types. Their cargo includes proteins, lipids, RNAs, and DNA, which reflect the physiological state of their cells of origin. Recently, urinary extracellular vesicles have emerged as a valuable source of biomarkers for kidney and systemic disease.Unfortunately, all existing methods for extracellular vesicle isolation from urine are time consuming and/or expensive. Thus, they are not adaptable to large-scale studies and unsuitable for clinical use without special equipment in the laboratory. Recently, our group has devised a s...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
ConclusionsDuring and following implementation of adult epo dosing guidelines, transfusion and anemia frequency increased in pediatric HD patients. Ideal target hemoglobin levels for pediatric dialysis patients warrant further study.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
This article focuses on the impact of chemical composition and structural properties of tofu-whey concentrates on their surface behavior at the air/water interface and foaming properties in acid medium. Liquid tofu-whey (pH 5.6 ± 0.1) was concentrated at three combinations of temperature and pressure (50 °C-8.0 kPa, 65 °C-16.0 kPa and 80 °C-24.0 kPa), with further dialysis (4 °C, 48 h) and freeze-drying, giving the samples TWC50, TWC65 and TWC80, respectively. The increase of temperature during the concentration step promoted the enrichment of the concentrates in crude protein and calcium, without ap...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 9 November 2019Source: Journal of Molecular BiologyAuthor(s): Tyler M. Marcinko, Chungwen Liang, Sergey Savinov, Jianhen Chen, Richard W. VachetAbstractIn dialysis patients, the protein β2-microglobulin (β2m) forms amyloid fibrils in a condition known as dialysis-related amyloidosis. To understand the early stages of the amyloid assembly process, we have used native electrospray ionization (ESI) together with ion mobility mass spectrometry (IM-MS) to study soluble pre-amyloid oligomers. ESI-IM-MS reveals the presence of multiple conformers for the dimer, tetramer, and hexamer th...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
(American Society of Nephrology) Patients receiving hemodialysis at facilities   located in residential areas with a high percentage of Black residents have a higher rate of hospitalization. Results from the study will be presented at ASN Kidney Week 2019 Nov. 5-10 at the Walter E. Washington Convention Center in Washington, D.C.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Authors: Hassuna NA, Mansour M, Ahmed TI, Hassan EA, Hefzy MM, Abd Elghani WM, Hefzy EM Abstract Background: T regulatory cells (Tregs), through variable mechanisms, play a crucial role in Hepatitis C virus (HCV) chronicity and infection tolerance. A great speculation is posed regarding the level, role of Tregs in end-stage renal disease (ESRD), and the presence of associated factors that could influence the Tregs population. Accordingly, we aimed at studying the effect of HCV infection on peripheral CD4+CD25+Tregs population among patients on hemodialysis (HD) as well as the effect of other comorbidities on these ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
We present a female case with congenital cataracts, severe intellectual impairment, sensorineural hearing loss, and renal tubular dysfunction as Lowe syndrome. A 9-year-old Japanese girl visited our hospital due to prolonged proteinuria. Her renal biopsy revealed diffuse mesangium proliferation, sclerosis and dilatation of renal tubules, and mild IgA deposition in the mesangial region. Furthermore, she had congenital cataracts, severe intellectual impairment, and sensorineural hearing loss. Genetic screening did not identify mutations of theORCL gene encoding inositol polyphosphate 5-phosphatase (IPP-5P) (46 XX, female). H...
Source: CEN Case Reports - Category: Urology & Nephrology Source Type: research
This study aimed to determine whether hemodialysis is associated with vitreous haemorrhage in patients with proliferative diabetic retinopathy. These results suggest that hemodialysis therapy does not seem to be a significant risk for vitreous haemorrhage in proliferative diabetic retinopathy patients. AbstractAims/IntroductionFor diabetes patients undergoing hemodialysis, vitreous hemorrhage seems to be a hemodialysis ‐induced hemorrhagic complication because of the effect of systemic anticoagulation. However, it is unclear whether hemodialysis is associated with vitreous hemorrhage in diabetes patients. We therefore ca...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
AstraZeneca said on Friday that safety data on roxadustat underpinned the British drugmaker's hopes for the anemia drug to become a standard treatment for patients with kidney disease.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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