Keeping the Holidays Allergy and Asthma-Free
Title: Keeping the Holidays Allergy and Asthma-FreeCategory: Health NewsCreated: 12/21/2017 12:00:00 AMLast Editorial Review: 12/22/2017 12:00:00 AM
ConclusionsClinical presentations are directly associated with inflammatory endotypes in CRS. Identification of inflammatory endotypes may allow for more precise and personalized medical treatments in CRS.
For patients with mild, persistent asthma and low levels of eosinophils, responses to two steroids were no better than response to placebo, new research shows.Medscape Medical News
Study question Is dampness and indoor mould associated with onset and remission of respiratory symptoms, asthma and rhinitis among adults? Materials and methods Associations between dampness, mould and mould odour at home and at work and respiratory health were investigated in a cohort of 11 506 adults from Iceland, Norway, Sweden, Denmark and Estonia. They answered a questionnaire at baseline and 10 years later, with questions on respiratory health, home and work environment. Results Baseline water damage, floor dampness, mould and mould odour at home were associated with onset of respiratory symptoms and asthma (O...
The microbiome of newborns, which can be affected by mode of delivery and alters again with feeding after birth, could predict wheezing later in life, new research shows.Medscape Medical News
CONCLUSION: Knowledge of the skin microbiome has improved in recent years. This will certainly improve the understanding of the pathogenesis causing atopic eczema. These findings may also form the foundation of new treatment and prevention strategies for atopic eczema in the future. PMID: 31111169 [PubMed - as supplied by publisher]
Publication date: Available online 21 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Elizabeth C. Matsui, Craig E. Pollack, Roger D. Peng, Corinne A. Keet
The interaction between asthma and infections is a complicated one, and that is the focus of this issue of the Immunology and Allergy Clinics of North America. Infections, both viral and bacterial, have been associated with development and exacerbation of asthma, while parasitic infections may actually help protect against asthma. Furthermore, as our drug armamentarium begins to focus on biologics, which can selectively impair components of the immune response, there is concern that treated patients with asthma will be at risk of developing opportunistic infections.
Severe lower respiratory tract infection in infants and young children is most frequently caused by respiratory syncytial virus (RSV). RSV infects the smallest airways, making breathing difficult and in some infants requiring medical support. Severity is affected by viral dose, infant age, virus genotype, and effectiveness of the innate/adaptive immune responses. Severe disease correlates with later wheezing and asthma in some children. The adaptive immune response is protective but wanes after each infection, likely due to the ability of the RSV NS1/NS2 proteins to inhibit the innate immune response. Several vaccine appro...
This article is protected by copyright. All rights reserved. PMID: 31112301 [PubMed - as supplied by publisher]
MicroRNA-21 (miR-21), probably one of the most studied miRNAs to date, is found pleiotropic in various biological events. Its emerging role in pulmonary remodeling has attracted extensive attention. This revie...