Experimental Inhibition of Periostin Attenuates Kidney Fibrosis.

CONCLUSION: Periostin is a marker of renal fibrosis and may augment the progression of fibrogenesis as an extracellular matrix protein. Periostin blockade effectively attenuated renal fibrogenesis. Thus, periostin inhibition may be a therapeutic strategy for the amelioration of renal disease progression.
PMID: 29268247 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - December 21, 2017 Category: Urology & Nephrology Authors: Hwang JH, Yang SH, Kim YC, Kim JH, An JN, Moon KC, Oh YK, Park JY, Kim DK, Kim YS, Lim CS, Lee JP Tags: Am J Nephrol Source Type: research