CX3CL1 promotes MMP-3 production via the CX3CR1, c-Raf, MEK, ERK, and NF- κB signaling pathway in osteoarthritis synovial fibroblasts

Osteoarthritis (OA) is a degenerative joint disease that affects the cartilage, synovium, and subchondral bone and is the leading cause of disability in older populations. Specific diagnostic biomarkers are la...

Source: Arthritis Research and Therapy - December 21, 2017 Category: Rheumatology Authors: Sheng-Mou Hou, Chun-Han Hou and Ju-Fang Liu Tags: Research article Source Type: research