FDA to Remove Boxed Warning From Some Asthma Meds
The FDA will remove a Boxed Warning from certain inhaled medications used to treat asthma and chronic obstructive pulmonary disease (COPD).
Authors: Satia I, Badri H, Lahousse L, Usmani OS, Spanevello A PMID: 30310687 [PubMed]
Authors: Quintos A, Naranjo M, Kelly C, Quan SF, Sharma S Abstract PURPOSE: The HoSMed Database recently demonstrated a high prevalence of obstructive sleep apnea (OSA) in hospitalized obese patients. Based on a long-term follow-up, this study showed an improved survival among patients who were adherent with the therapy. In this post-hoc analysis we explore the characteristics, associations, and mortality outcome of OSA in the African American (AA) population. METHODS: These subset analyses included obese AA patients screened in the hospital as high-risk for OSA. Stepwise logistic regression analysis was used t...
Publication date: Available online 9 October 2018Source: Pharmacological ResearchAuthor(s): D. Visca, P. Pignatti, A. Spanevello, E. Lucini, E. La RoccaAbstractDiabetes is a common metabolic disorder affecting the entire body with high morbidity and mortality worldwide. The major complications related to diabetes are mostly due to the macrovascular and microvascular bed impairment due to metabolic, hemodynamic and inflammatory factors. However, studies over the past decades have added also the lung as a target organ in both type 1 and type 2 diabetes. Diabetes has always been addressed as a major comorbidity conditioning t...
Albuminuria linked to increased risk for COPD and COPD - related events but not asthma
ConclusionThe scope of the present review is to explore the inflammatory mechanism in airway diseases and highlight the influence of aging on airways ’ inflammation mechanism. The main goal of this review is to encourage research collaborations between experimentalist and modelers to promote our understanding of the physiological and pathological mechanisms that control inflammation in different airway diseases.
CONCLUSIONS: Asthma patients with FAO had a smaller LA and higher resistance of the proximal airways than COPD patients. FEV1 and respiratory impedance correlated with airway morphology.
Lung ultrasound can accelerate the diagnosis of life-threatening diseases in adults with respiratory symptoms.
PMID: 30314689 [PubMed - as supplied by publisher]
Abstract To prevent unnecessary use of inhaled corticosteroids (ICS), ICS treatment should only be started when the diagnostic process of asthma and COPD is completed. Little is known about the chronological order between these diagnoses and the start of ICS. We performed a retrospective cohort study, based on electronic medical records of 178 Dutch general practices, to explore the temporal relations between starting continuous use of ICS and receiving a diagnosis of asthma and/or COPD. The database included information of patients who were registered with a diagnosis of asthma and/or COPD in one of the practices...
Dr Navitha Ramesh provides her perspective on how best to treat patients with these dual airway diseases.CHEST and Medscape