Association of Low-Moderate Arsenic Exposure and Arsenic Metabolism with Incident Diabetes and Insulin Resistance in the Strong Heart Family Study

Conclusions:
Among participants without baseline prediabetes, arsenic exposure was associated with incident diabetes. Low MMA% was cross-sectional and prospectively associated with higher HOMA2-IR. Research is needed to confirm possible interactions of arsenic metabolism with B vitamins and AS3MT variants on diabetes risk. https://doi.org/10.1289/EHP2566

Received: 23 July 2017
Revised: 30 October 2017
Accepted: 7 November 2017
Published: 20 December 2017

Address correspondence to M. Grau-Perez, Columbia University Mailman School of Public Health, 722 W. 168th St., Room 1105, New York, NY 10032. Telephone: [phone]. Email: [e-mail], or A. Navas-Acien, Columbia University Mailman School of Public Health, 722 W. 168th St., Room 1105, New York, NY 10032. Telephone: [phone]. Email: [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP2566).
The authors declare they have no actual or potential competing financial interests.
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Supplemental Materia...

Source: EHP Research - December 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research