Could delirium and anti-dementia drugs effect the treatment of agitated nursing home residents with Alzheimer dementia?

In a recent issue of Journal of the American Medical Directors Association, Viscogliosi et  al have achieved important results in testing safer and more effective alternatives in the treatment of agitation in nursing home residents with Alzheimer dementia (AD).1 There is insufficient data on the comparison of citalopram with antipsychotics in this regard, indicating that this study could make important contributions for beneficial treatment options in agitation improvement in AD patients. Besides, the authors may not have considered a few factors that could affect the results in the adjusted analysis.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Letter to the Editor Source Type: research

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CONCLUSIONS: BPMSE has a limited predictive value for the variables studied. PMID: 31739306 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Funding Opportunity RFA-NS-20-012 from the NIH Guide for Grants and Contracts. This initiative will provide two years of support for planning activities necessary for initiating a Phase III clinical trial designed to validate VCID biomarkers and/or treat patients with VCID. The full spectrum of VCID is in scope, and the one or more VCID disorders(s) to be targeted in the trial must be clearly specified in the application, for example (but not limited to): vascular insults including clinical stroke, silent infarcts and microinfarcts, leukoaraiosis, cerebral amyloid angiopathy (CAA), transient ischemic attack (TIA), micro-b...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer. My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true. Seven years ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Alzheimer's Disease Source Type: news
DEMENTIA, in particular Alzheimer ’s disease, effects 850,000 people in the UK. This figure is set to rise to two million by 2015. There is currently no cure for dementia, however, a new study has suggested Alzheimer’s disease could be predicted by a brain scan decades before symptoms develop.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
We present here the development of an electrochemical immunosensor based on nanostructured screen-printed carbon electrodes for the quantification of unfolded p53 in plasma samples. The sensor shows a suitable linear range (from 2 to 50 nM) for its application in real blood samples and a very low limit of detection (0.05 nM). The concentration of unfolded p53 has been accurately detected in plasma of elderly people in healthy conditions, subjects with mild cognitive impairment (MCI) and Alzheimer's Disease (AD) subjects, obtaining results with no significant differences to those provided by an ELISA assay. These result...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
This report, commissioned by Alzheimer ’s Society, provides projections of the number of older people (aged 65 and over) living with dementia and the costs of health care, social care and unpaid care for older people living with dementia from 2019 to 2040 in the UK.
Source: NHS Networks - Category: UK Health Source Type: news
In 2016, UC San Francisco researchers discovered mice with an Alzheimer's risk gene had fewer 'sharp-wave ripples.' Their new study suggests these memory waves can predict dementia 30 years early.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conditions:   Mild Cognitive Impairment;   Dementia;   Intermittent Claudication Intervention:   Behavioral: Leg ischemia Sponsors:   Aristotle University Of Thessaloniki;   Greek Alzheimer's Association and Related Disorders Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: November 2019Source: Alzheimer's &Dementia, Volume 15, Issue 11Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: November 2019Source: Alzheimer's &Dementia, Volume 15, Issue 11Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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