GERD Associated with Increased Risk for Head and Neck Cancers

Gastroesophageal reflux disease (GERD) is associated with significantly increased risk for cancers of the upper aerodigestive tract in older adults, according to a case-control...
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news

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Publication date: Available online 5 August 2020Source: American Journal of OtolaryngologyAuthor(s): Annica C. Eells, Christopher Mackintosh, Lisa Marks, Michael J. Marino
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Authors: Yin CY, Zhang SS, Zhong JT, Zhou SH Abstract Laryngeal and hypopharyngeal carcinomas are common malignant tumors of the head and neck, which are both exhibiting increasing incidences. Laryngopharyngeal reflux is the retrograde flow of gastric contents into the larynx, oropharynx, and/or nasopharynx. There remains controversy regarding whether laryngopharyngeal reflux is a risk factor for laryngeal and hypopharyngeal cancers. The refluxing substances mainly include hydrochloric acid, pepsin, and occasionally bile acids and bile salts, as well as bacteria that colonize the gastrointestinal tract. Loss of epi...
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
In this study, visual simulation scale and general comfort questionnaire developed by Kolaba, an American comfort nursing specialist, were used to evaluate the comfort level of the 2 groups of patients, including pain, acid reflux, upper abdominal burning sensation, and hiccup. Objective indexes such as height, body mass index, albumin value, electrolyte, wound healing, and pharyngeal fistula were used to evaluate the prognosis of the 2 groups of patients. The visual simulation scale can preliminarily judge the subjective feelings of patients. Trial registration: It has been registered at
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
When a toddler presented with a raspy voice, pediatricians initially suspected respiratory infections, dysphonia and then acid reflux. But, as revealed in a “Mystery Diagnosis” column in the Washington Post, the problem was much more serious. A pediatrician initiated acid reflux treatment and referred the little girl, who had experienced voice problems since birth, to a a pediatric otolaryngologist.  The ENTs investigations revealed a diagnosis that shocked the girls’ parents: She had a rare disease—recurrent respiratory papillomatosis. Caused by two strains of the human papilloma virus (HPV)&m...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - Category: Speech-Language Pathology Authors: Tags: Health Care News Slider Speech-Language Pathology HPV Voice Disorders Source Type: blogs
Abstract To compare safety and effectiveness of prolonged (>28 days) versus short duration (≤28 days) use of nasogastric tube for enteral nutrition and weight loss prevention during curative radiotherapy with or without concurrent chemotherapy or cetuximab for head and neck cancer patients. We performed a retrospective study and database review of all patients at our center, treated with radiotherapy for head and neck cancer receiving enteral nutrition by nasogastric tube. Type of treatment, weight and body mass index changes, and related complications (gastroesophageal reflux, pneumonia, ulcer, feeding tube...
Source: Nutrition and Cancer - Category: Cancer & Oncology Authors: Tags: Nutr Cancer Source Type: research
Abstract INTRODUCTION: The aim of this study was to evaluate the current indications for and clinical factors influencing the use of transnasal esophagoscopy (TNE). METHODS: An online survey was sent to American Broncho-Esophagological Association members, including questions on demographics, indications, and factors influencing the use of TNE. RESULTS: Sixty of 251 members (24%) completed the survey. Ninety-three percent of respondents reported academic practices, while 98% practice in medium to large urban settings. Thirty-five (58%) completed laryngology fellowships. Mean monthly TNE procedure count was 7.15 (range,
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
CONCLUSION: There is novel evidence that acidic bile-induced NF-κB-related oncogenic mRNA and miRNA phenotypes are generated after short-term 7-day mucosal exposure and that topical mucosal application of BAY 11-7082 can prevent the acidic bile-induced molecular alterations associated with unregulated cell growth and proliferation of hypopharyngeal cells. PMID: 29529473 [PubMed - as supplied by publisher]
Source: Neoplasia - Category: Cancer & Oncology Authors: Tags: Neoplasia Source Type: research
Conclusion: Overall, Amenity Health has created a very high quality product in their MedCline Reflux Relief System. It effectively prevents reflux and is, in my opinion, more comfortable than the more traditional wedges on the market. However, higher...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive GI Medicine Source Type: blogs
A new study finds a strong association between acid reflux and cancers of the respiratory and upper digestive tracts in older adults.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
New research suggests people with chronic acid reflux might have higher odds for even more dangerous foes -- head and neck cancers
Source: WebMD Health - Category: Consumer Health News Source Type: news
More News: Acid Reflux | Cancer | Cancer & Oncology | Gastroenterology | Gastroesophageal Reflux Disease | GERD | Head and Neck Cancer | Primary Care