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Mild Low Thyroid Levels May Affect a Woman's Fertility

Source: HealthDay Related MedlinePlus Pages: Female Infertility, Hypothyroidism
Source: MedlinePlus Health News - Category: Consumer Health News Source Type: news

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CONCLUSION: For sure, the therapeutic regimens used for controlled ovarian hyperstimulation (COH) induce a deterioration of thyroid function in patients suffering from TAI [with or without Levothyroxine (LT4) treatment]. This picture places patients in a condition of increased risk of developing untimely TSH elevation during fertilization; then, it is reasonable that a patient, above all if thyroid antibody positive, would have a TSH value
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Endocrinology Authors: Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
ConclusionIn the patients with Hashimoto’s disease, preconception LT4 treatment may relieve adverse effects, including autoimmune antibodies, and support follicular development.
Source: Journal of Obstetrics and Gynaecology Research - Category: OBGYN Authors: Tags: Original Article Source Type: research
Publication date: Available online 12 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Simone De Leo, Elizabeth N Pearce Understanding of changes in thyroid function and the consequences of thyroid disease during pregnancy has rapidly grown in the past two decades, and revised American Thyroid Association guidelines on this topic were published in 2017. This Review explores the association between thyroid autoimmunity and complications during and after pregnancy. Thyroid autoimmunity refers to the presence of antibodies to thyroperoxidase or thyroglobulin, or thyroid-stimulating hormone receptor ant...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
ConclusionsIn view of the high prevalence of thyrotoxicosis and hypothyroidism, a considerable part of infertile patients may harbor overt or subclinical thyroid disease. Identification and management of thyrotoxicosis/hypothyroidism associated infertility needs the collaboration of andrologists, endocrinologists, gynecologists, and general practitioners.
Source: Endocrine - Category: Endocrinology Source Type: research
Mutations in the gene CHD7 cause CHARGE syndrome, a rare multi‐organ syndromic disorder. Gonadal defects are common in individuals with CHARGE syndrome (seen in ∼60–80% of cases) and represent the letter “G” in the CHARGE syndrome acronym. The gonadal defect in CHARGE syndrome results from congenital deficiency of the hypothalamic hormone Gonadotropin‐releasing hormone (GnRH), which manifests clinically as pubertal failure and infertility, and biochemically as hypogonadotropic hypogonadism (low sex steroid hormone levels with inappropriately normal or low gonadotropin levels). In addition to the g...
Source: American Journal of Medical Genetics Part C: Seminars in Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: RESEARCH REVIEW Source Type: research
Conclusions: Using IVF to investigate human reproduction and pregnancy outcomes, we found that concentrations of some urinary PFR metabolites were negatively associated with proportions of successful fertilization, implantation, clinical pregnancy, and live birth. https://doi.org/10.1289/EHP1021 Received: 26 August 2016 Revised: 10 April 2017 Accepted: 02 June 2017 Published: 25 August 2017 Address correspondence to C. Carignan, Department of Environmental Health, Building 1, 14th Floor, 665 Huntington Avenue, Boston, MA 02115 USA. Phone: (617) 432-4572. Email: carignan@hsph.harvard.edu Supplemental Material is avail...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
AbstractMonitoring subclinical hypothyroidism (SCH) in women is believed to be important in terms of preventing overt hypothyroidism and optimizing the health and cognitive development of their children. Current systematic reviews have suggested an association between maternal SCH and adverse obstetric and neonatal outcomes. However, initiating the administration of thyroxine during pregnancy has failed to demonstrate appreciable health benefits. Hence there are calls by professional endocrine societies for optimizing serum thyroid-stimulating hormone (TSH) levels pre-conception. The strategy of ensuring that serum TSH lev...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
Authors: Rao A, Jain D, Aggarwal HK, Jain P Abstract Klinefelter's syndrome is the most common chromosomal disorder associated with testicular dysfunction and male infertility. Those affected by Klinefelter's syndrome are at increased risk of systemic lupus erythematosus, breast cancer, non-Hodgkin's lymphoma, and lung cancer. Nephrotic syndrome in association with Klinefelter's syndrome has never been reported in the literature. PMID: 28675185 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research
Conclusions: Certain PFASs are associated with abnormal menstruation in humans. https://doi.org/10.1289/EHP1203 Received: 08 October 2016 Revised: 03 January 2017 Accepted: 25 January 2017 Published: 22 June 2017 Address correspondence to J. Zhang, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. Telephone: 86-21-2507 8871. E-mail: junjimzhang@sina.com, or Y. Tao, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. Telephone: 86-21-663846590-776806. E-mail: taoyx@163.com Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Abstract Context • Subclinical hypothyroidism (SCH) in pregnancy can be associated with increased complications in pregnant women and neurocognitive deficits in fetuses. Two recently published meta-analyses investigated the effects of levothyroxine (LT4) supplementation on pregnancy outcomes but did not report adverse complications and neonatal outcomes. Objectives • The study intended to assess the effects of LT4 supplementation in the treatment of pregnant women with thyroid dysfunction. Design • The research team performed a meta-analysis of randomized controlled trials (RCTs) published in PubMed...
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research
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