Measurement of effective detective quantum efficiency for a photon counting scanning mammography system and comparison with two flat panel full-field digital mammography systems.

Measurement of effective detective quantum efficiency for a photon counting scanning mammography system and comparison with two flat panel full-field digital mammography systems. Phys Med Biol. 2017 Dec 20;: Authors: Wood TJ, Moore CS, Saunderson JR, Beavis AW Abstract Effective Detective Quantum Efficiency (eDQE) describes the resolution and noise properties of an imaging system along with scatter and primary transmission, all measured under clinically appropriate conditions. Effective dose efficiency (eDE) is the eDQE normalised to mean glandular dose and has been proposed as a useful metric for the optimisation of clinical imaging systems. The aim of this study was to develop a methodology for measuring eDQE and eDE on a Philips MicroDose Mammography (MDM) L30 photon counting scanning system, and to compare performance with two conventional flat panel systems. A custom made lead-blocker was manufactured to enable the accurate determination of dose measurements, and modulation transfer functions were determined free-in-air at heights of 2, 4 and 6 cm above the breast support platform. eDQE were calculated for a Philips MDM L30, Hologic Dimensions and Siemens Inspiration digital mammography system for 2, 4 and 6 cm thick poly(methyl methacrylate) (PMMA). The beam qualities (target/filter and kilovoltage) assessed were those selected by the automatic exposure control, and anti-scatter grids were used where available. Measurements of eDQE demons...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research

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Kaiser Permanente of the Mid-Atlantic States begins seeing patients at its new Haymarket medical center Monday. The new Prince William County facility, first announced in June 2018, comprises 36,423 square feet for primary care, OB-GYN, clinical lab, pharmacy, optometry and behavioral health services, in addition to imaging services like general radiology, bone density scanning and mammography. And beyond those services, the system is tapping technology, like video conferencing, for patients to…
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
AbstractBackgroundThe density of tumor-infiltrating lymphocytes (TIL) is a predictive factor for response to neoadjuvant systemic therapy (NAST) in breast cancer. High TIL density correlates with higher complete pathologic remission (pCR) in triple negative and HER2 positive breast cancer. Additionally, not only TIL density but also subsets of immune cells in tumor stroma seem to play an important role in cancer and immune cell interaction and response to chemotherapy. Our aim is to determine TIL density and expression of CD 20, CD3, CD8, PD-L1, FOXP3 and PGM1 on core biopsy specimen and find a correlation with pCR.Trial d...
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
ConclusionConventional BC-imaging modalities have both advantages and limitations. When utilized in combination, they are often complementary. For example, a limitation of mammography is low sensitivity in dense breasts. The addition of DBT lessens this limitation by providing three-dimensional (3D) images of the breast that minimizes the effect of overlying breast tissue. Additionally, US added to mammography in dense breasts increases screening sensitivity and has the advantages of accessibility and lack of ionizing radiation. MRI is currently the most sensitive method used for detecting BC. When MRI is not suitable for ...
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research
Publication date: Available online 16 September 2019Source: European Journal of RadiologyAuthor(s): Haijie Li, Lu Yin, Ni He, Peng Han, Yueqiang Zhu, Yue Ma, Aidi Liu, Hong Lu, Zhipeng Gao, Peifang Liu, Yaopan Wu, Zhaoxiang YeAbstractPurposeTo compare the comfort levels of cone beam breast computed tomography (CBBCT) and digital mammography.Materials and MethodsOn 409 patients, CBBCT was performed within 1 week after conventional mammography. Patients evaluated their comfort by using an 11-point numerical rating scale (NRS-11) after completing the two examinations. The lower the score was, the more comfortable the examinat...
Source: European Journal of Radiology - Category: Radiology Source Type: research
A 68-year-old women presented with a right breast mass in the last 6 months, which was gradually increasing in size. Physical examination revealed a 10  cm mass in the upper outer quadrant of the right breast. This mass was firm, oval, non-tender, and free from the skin and underlying tissue. The medio-lateral mammogram revealed a homogenous dense, well-circumscribed lesion in the right breast (Fig. 1). In the axial thorax CT-scan image, we found a hypodense, well-defined mass with capsular wall of 7 cm containing endogenous daughter cysts (Fig.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Medical Imagery Source Type: research
ConclusionsA novel system using supine MRI images co-registered with intraoperative optical scanning and tracking enabled tumors to be resected with a trend toward a lower positive margin rate compared with wire-localized partial mastectomy. Margin positivity was more likely when imaging underestimated pathologic tumor size.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Condition:   Breast Cancer Screening Intervention:   Diagnostic Test: QT Scanner Sponsors:   QT Ultrasound LLC;   Analysis Group, Inc. Recruiting
Source: - Category: Research Source Type: clinical trials
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