An open-label, prospective, observational study of the efficacy of bisphosphonate therapy for painful osteoid osteoma

ConclusionsIn 17/23 patients with painful OO managed conservatively with bisphosphonates, long-term final success was achieved. Bisphosphonates may accelerate the spontaneous healing of OO.Key points•19/23 patients with OO managed with bisphosphonates experienced significant pain relief•Pain relief was sustained in 17/23 patients, mean follow-up of 36 months•CT demonstrated a significant increase in nidus mineralisation•MRI demonstrated a significant decrease in bone marrow oedema•Bisphosphonate therapy may accelerate the spontaneous healing of OO
Source: European Radiology - Category: Radiology Source Type: research