Breast and gynecological cancer patients' risk factors associated with biopsychosocial problem ‐related distress

Abstract ObjectivesInequalities exist between breast and gynecological cancer patients' experiences, leading to high levels of distress throughout the cancer journey. The present study aims to identify differences in source of biopsychosocial problem‐related distress between women diagnosed with breast or gynecological cancers. MethodsFrom 2009 to 2016, women with breast (n = 2111) and gynecological (n = 641) cancers were screened using the core items of the instrument You, Your Family, and City of Hope are a Team. This is a touch screen–based instrument that assess problem‐related distress due to physical, practical, functional, emotional, and other problems and identifies types of assistance requested. Data were analyzed using the linear regression model. ResultsA significant difference in overall biopsychosocial problems rated as high distress was found between breast (M = 5.0) and gynecological (M = 6.2) cancer patients (P 
Source: Psycho-Oncology - Category: Cancer & Oncology Authors: Tags: PAPER Source Type: research

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The present consensus on the inheritance of longevity is that genetic influences over aging only rise to importance in later life. Even then it is perhaps more a matter of resistance to accumulated molecular damage and its consequences than a slower pace of aging per se. Environment and choice throughout life are the overwhelming determinants of the course of aging leading into middle age, meaning exposure to pathogens, amount of visceral fat tissue, smoking, and similar line items. That of course raises the question as to the degree to which inherited longevity is a cultural rather than genetic phenomenon. Only a tiny min...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Abstract The 21st century has witnessed the discovery of multiple rare and common gene variants associated with attention deficit hyperactivity disorder (ADHD), and these discoveries have already provided a starting point for the investigation of the biology of the disorder and novel treatments. The purpose of this selective review is to examine genetic findings from the past 5 years and consider their implications for the conceptualization of ADHD and future clinical practice. Recent discoveries reveal the strong genetic overlaps between ADHD and autism spectrum disorder (ASD) as well as intellectual disability. ...
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research
A few days ago, a friend indicated on her Facebook page that she had “run out of spoons” and asked for support and energy to be sent her way. I had heard the term but didn’t know what it meant, so I turned to Google and typed in those words and what came up was the explanation that came from a conversation between two friends, one of whom had Lupus. Christine Miserandino was sitting at a table with her college roommate who asked her what it was like to have a disease that for many people would be considered invisible since overt symptoms may be elusive to the casual observer. Christine pondered for an e...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Caregivers Inspiration & Hope Motivation and Inspiration Policy and Advocacy Stigma alone time caregiving Disability Disability Advocacy energy Rejuvenation Source Type: blogs
According to the American Heart/American Stroke Association, stroke affects nearly 800,000 people in the United States each year. It is the fifth leading cause of death, and the leading cause of long-term disability.  It’s also the leading cause of preventable disability. In China it is the leading cause of death surpassing both cancer and heart disease. Stroke occurs when a blood vessel carrying oxygen and nutrients to the brain is either blocked by a blood clot or plaque (ischemic stroke), or…
Source: Health Care News Headlines - Category: Health Management Authors: Source Type: news
To investigate the opioid prescription patterns for adults with longstanding physical disability and inflammatory conditions, compared to a mixed group of other opioid users, after excluding cancer patients.
Source: Archives of Physical Medicine and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
An enhanced RRM2 siRNA delivery to rheumatoid arthritis fibroblast-like synoviocytes through a liposome‑protamine-DNA-siRNA complex with cell permeable peptides. Int J Mol Med. 2018 Aug 08;: Authors: Wang X, Wang X, Sun J, Fu S Abstract Rheumatoid arthritis (RA) is considered to be a systemic autoimmune disease that induces systemic complications and progressive disability. It affects a large number of people. RA fibroblast‑like synoviocytes (RA‑FLS) promote the progression of RA through the secretion of proinflammatory cytokines and increasing invasiveness into the extracellular matrix. Therefo...
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
Prostate cancer (CaP) in men represents the main cancer cause of years lost due to disabilities in most European countries [1]. Theoretically, focal therapy of CaP enables both cancer control and low treatment related side effects, leading to a reduction of years lost due to disabilities.
Source: Urologic Oncology: Seminars and Original Investigations - Category: Urology & Nephrology Authors: Tags: Original article Source Type: research
In this study, we analyzed FGF21 levels and alterations in the expression of genes encoding components of the FGF21-responsive molecular machinery in adipose tissue from aged individuals so as to ascertain whether altered FGF21 responsiveness that develops with aging jeopardizes human health and/or accelerates metabolic disturbances associated with aging. We studied a cohort of 28 healthy elderly individuals (≥70 years) with no overt signs of metabolic or other pathologies and compared them with a cohort of 35 young healthy controls (≤40 years). Serum FGF21 levels were significantly increased in elderly indiv...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
When specialists fail to accurately communicate important patient information,it can have enormous repercussions on that patient ’s health along with lasting legal consequences. According to the non-profit healthcare accreditation organization, Joint Commission, 70 percentof “adverse health outcomes” derive from failed physician communication. In an opinion piece published in theJournal of the American College of Radiology,radiologist Leonard Berlin examined how lack of specialist communication plays out in malpractice lawsuits and physician relationships.Dr. Berlin describes a lawsuit in which a 53-...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Conclusions: In total, DALYs 6 cancer diseases due to secondhand smoke analyzed in this study were 283,360 DALYs. Thus, the results of the research can be used as a basis for further policies making on national cigarette prevention and control in Indonesia. PMID: 30051678 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
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