Prognostic value of GRIM-19, NF- κB and IKK2 in patients with high-grade serous ovarian cancer.

CONCLUSIONS: GRIM-19 is a potential predictor of prognosis and disease recurrence in HGSC. IKK2 and NF-κB are related to poor prognosis and are potential predictors of response to platinum-based chemotherapy in HGSC. IHC analyses of GRIM19, IKK2 and NF-κB may be important in the attempt to provide prognostic values for relapse and response to treatment in patients with HGSC.
PMID: 29254797 [PubMed - as supplied by publisher]

Source: Pathology, Research and Practice - December 6, 2017 Category: Pathology Authors: Ilelis F, do Amaral NS, Alves MR, da Costa AABA, Calsavara VF, Lordello L, De Brot L, Soares FA, Rodrigues IS, Rocha RM Tags: Pathol Res Pract Source Type: research