Cognitive impairment and cardiovascular diseases in the elderly. A heart-brain continuum hypothesis.

Cognitive impairment and cardiovascular diseases in the elderly. A heart-brain continuum hypothesis.
Ageing Res Rev. 2014 Aug 5;
Authors: Abete P, Della-Morte D, Gargiulo G, Basile C, Langellotto A, Galizia G, Testa G, Vincenzo C, Bonaduce D, Cacciatore F
Abstract
The ageing population is increasing and, therefore, a higher prevalence of cardiac disease is emerging; including hypertension, coronary artery disease, atrial fibrillation and chronic heart failure. Large cohort studies have revealed a relationship among increased risk for cognitive impairment and dementia in cardiovascular diseases probably due to embolic stroke or chronic cerebral hypoperfusion. Thus, the aim of the present review is to overview the studies that investigate the presence and/or the development of cognitive impairments and dementia in patients with varied types of cardiovascular disease. Finally, a continuum among hypertension, coronary artery disease, atrial fibrillation and chronic heart failure with to the development of cognitive impairment and progression to dementia has been hypothesized.
PMID: 25107566 [PubMed - as supplied by publisher]

Source: Ageing Research Reviews - August 5, 2014 Category: Genetics & Stem Cells Authors: Abete P, Della-Morte D, Gargiulo G, Basile C, Langellotto A, Galizia G, Testa G, Vincenzo C, Bonaduce D, Cacciatore F Tags: Ageing Res Rev Source Type: research