Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide.

Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide.
Neth J Med. 2017 Dec;75(10):451-454
Authors: van der Vlist A, Snijders TJ, Stades AME, Spliet WGM, De Vos FYFL
Abstract
A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.
PMID: 29256415 [PubMed - in process]

Source: The Netherlands Journal of Medicine - December 1, 2017 Category: General Medicine Authors: van der Vlist A, Snijders TJ, Stades AME, Spliet WGM, De Vos FYFL Tags: Neth J Med Source Type: research