(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.7b01584

Source: Journal of Medicinal Chemistry - December 20, 2017 Category: Chemistry Authors: Emanuele Amata, Antonio Rescifina, Orazio Prezzavento, Emanuela Arena, Maria Dichiara, Valeria Pittala ̀, Ángeles Montilla-García, Francesco Punzo, Pedro Merino, Enrique J. Cobos and Agostino Marrazzo Source Type: research