Log in to search using one of your social media accounts:


The Sister Study Cohort: Baseline Methods and Participant Characteristics

Author Affiliations open 1Epidemiology Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA 2Social &Scientific Systems, Inc., Durham, North Carolina, USA 3Westat, Durham, North Carolina, USA 4Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway 5Biostatistics and Computational Biology Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA PDF Version (548 KB) Abstract About This Article Supplemental Material Background: The Sister Study was designed to address gaps in the study of environment and breast cancer by taking advantage of more frequent breast cancer diagnoses among women with a sister history of breast cancer and the presumed enrichment of shared environmental and genetic exposures. Objective: The Sister Study sought a large cohort of women never diagnosed with breast cancer but who had a sister (full or half) diagnosed with breast cancer. Methods: A multifaceted national effort employed novel strategies to recruit a diverse cohort, and collected biological and environmental samples and extensive data on potential breast cancer risk factors. Results: The Sister Study enrolled 50,884 U.S. and Puerto Rican women 35–74 y of age (median 56 y). Although the majority were non-Hispanic white, well educated, and economically well off, substantial numbers o...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

Related Links:

Acontroversial study recently published inJAMA Pediatrics has posed possible but largely unfounded links between autism and ultrasound technique and frequency. According to researchers from Boston University School of Medicine, there is a possible correlation between depth of ultrasound penetration during the first and second trimesters and autism. The researchers evaluated sonograms of 420 children, 107 with autism, 104 with developmental delay, and 209 with typical development. They looked at the frequency of ultrasound scans and penetration depth amongst the three groups. They found that mothers of children with au...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
This debate pack outlines progress so far in implementing the cancer strategy and provides statistics on survival rates and the NHS cancer workforce. It also collates commentary and analysis from official, parliamentary and third sector organisations.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
ABSTRACT Deciphering the complex milieu that makes up the tumor microenvironment (TME) and the signaling engaged by TME cytokines continues to provide novel targets for therapeutic intervention. The IL‐6 family member Oncostatin M (OSM) has recently emerged as a potent driver of tumorigenesis, metastasis and therapy failure, molecular programs most frequently attributed to IL‐6 itself. In a recent issue of The Journal of Pathology, Kucia‐Tran et al. describe how elevated Oncostatin M receptor (OSMR) expression results in a feed‐forward loop involving the de novo production of both OSM and OSMR to facilitate aggress...
Source: The Journal of Pathology - Category: Pathology Authors: Tags: Invited Commentary Source Type: research
Authors: Thompson DA, Federspiel DA Abstract Darcy A Thompson is an Associate Professor of pediatrics at the University of Colorado School of Medicine. Her main research seeks to address early childhood obesity in low-income children. She works in the Lifestyle Medicine clinic at Children's Hospital Colorado, a clinic focused on caring for children with obesity and related comorbidities. She is also an Associate Medical Director for the Research Institute at Children's Hospital Colorado. Her training includes a Master of Public Health degree, a medical degree (Yale University) and the Robert Wood Johnson Clini...
Source: Journal of Comparative Effectiveness Research - Category: General Medicine Tags: J Comp Eff Res Source Type: research
This NIHR Signal finds that for western high-income countries such as the UK, an estimated 15% to 16% of cancers could be avoided by preventing diabetes, obesity or excess weight. Although the links between high BMI, diabetes and cancer have been known for some time, this study presents the first calculations of attributable risk for 175 countries. This represents the proportion of cancers that could be prevented if the risk factors were eliminated.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Conclusions: Patients with scleral flaps created for biopsy of uveal melanoma are at risk for scleral thinning and extrascleral extension of tumor recurrence through the flap.Ocul Oncol Pathol
Source: Ocular Oncology and Pathology - Category: Opthalmology Source Type: research
This article is protected by copyright. All rights reserved.
Source: BJOG: An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: Mini ‐commentary Source Type: research
According to this study: Current or recent users of hormonal contraceptives are at higher risk for breast cancer than women who have never used hormonal contraceptives.The risk increases with the duration of use.
Source: AJN - Category: Nursing Tags: Journal Watch Source Type: research
According to this study: Coffee drinking is more often associated with benefit than harm for a range of health outcomes.The only consistent evidence of harm was regarding pregnancy outcomes and risk of bone fracture in women.
Source: AJN - Category: Nursing Tags: Journal Watch Source Type: research
Oncology Nurses' Knowledge, Confidence, and Practice in Addressing Caregiver Strain and Burden
. Oncol Nurs Forum. 2018 Mar 01;45(2):187-196 Authors: Irwin MM, Dudley W, Northouse L, Berry DL, Mallory GA Abstract OBJECTIVES: To describe nurses' practices, confidence, and knowledge of evidence-based interventions for cancer caregiver strain and burden and to identify factors that contribute to these aspects. 
. SAMPLE & SETTING: 2,055 Oncology Nursing Society members completed an emailed survey.
. METHODS & VARIABLES: Pooled analysis of survey results. Variables included the bas...
Source: Ann Oncol - Category: Cancer & Oncology Authors: Tags: Oncol Nurs Forum Source Type: research
More News: Acne | Alcoholism | Appendicitis | Babies | Biology | Brain | Breast Cancer | Breast Carcinoma | Breast Lumpectomy | Breast Needle Aspiration | Canada Health | Cancer | Cancer & Oncology | Carcinoma | Carcinoma in Situ | Chemistry | Child Development | Childhood Cancer | Children | Colon Cancer | Colorectal Cancer | Computers | Conferences | Databases & Libraries | DCIS (Ductal Carcinoma in Situ) | Diets | Disability | Ductal Carcinoma | Education | Environmental Health | Epidemiology | Genetics | Georgia Health | Grants | Health Management | Hormonal Therapy | Hormones | Hysterectomy | International Medicine & Public Health | Laboratory Medicine | Learning | Legislation | Lobular Carcinoma | Lumpectomy | Mammography | Mastectomy | Melanoma | Men | Menopause | Neurology | Neuroscience | Neurosurgery | Nonmelanoma Skin Cancer | Norway Health | Nursing | Nutrition | Obesity | Occupational Health | Oral Cancer | Ovarian Cancer | Ovaries | Papanicolaou (Pap) Smear | Pathology | PET Scan | Phlebotomy | Poland Health | Pregnancy | Pregnancy and Breast Cancer | Primary Care | Reproduction Medicine | Science | Sigmoidoscopy | Skin | Skin Biopsy | Skin Cancer | Sleep Disorders | Sleep Medicine | Smokers | Spain Health | Statistics | Study | Universities & Medical Training | USA Health | Vitamin D | Vitamins | Websites | Women