Skyline Medical to take 20% stake in Helomics, license Illumina ’ s gene sequencing tech

Fresh from its purchase of a 20% stake in joint venture partner Helomics, Skyline Medical (NSDQ:SKLN) said today that it inked a deal to license the MiSeqDx next-generation sequencing technology from Illumina (NSDQ:ILMN). Yesterday Minneapolis-based Skyline said it agreed to buy a lump of convertible shares representing 20% of Helomics, in exchange for 1.1 million newly issued SKLN shares, which combined with its existing right to convert a $500,000 loan would give it a 25% stake in the Pittsburgh-based precision diagnostics and contract research firm. Yesterday’s $1.14 closing price for Skyline stock would value the 20% stake at nearly $1.3 million. “Our strategic growth plan is to invest in, and partner with, leading edge players in emerging areas of the healthcare industry to secure additional income streams and grow the value of Skyline,” CEO Dr. Carl Schwartz said in prepared remarks. “Helomics’ ability to offer data collection, analysis and actionable insights to BioPharma companies as they develop new cancer treatments, positions it as a highly-valuable partner to the fast-growing precision medicine sector. We are pleased to expand our relationship with Helomics through this investment and look forward to helping Helomics’ management to further commercialize its offering.” “Precise analysis of cancer tumors can deliver invaluable insights for cancer diagnostics and aid in the development of target...
Source: Mass Device - Category: Medical Devices Authors: Tags: Diagnostics Genomics Molecular Diagnostics Mergers & Acquisitions Helomics Illumina Inc. Skyline Medical Source Type: news

Related Links:

Cancer research will accelerate meaningfully towards the goal of control of all cancer only when a majority of researchers are working on mechanisms common to large number of different cancer types. There are too many subtypes of cancer and too few scientists to make real progress when tackling cancers one by one. Shutting down metastasis is one grail of cancer research, as the majority of cancer deaths are caused when cancer spreads throughout the body, not by the initial tumor. Thus a search for common mechanisms of metastasis is one of the few presently viable approaches to the production of broader cancer therapies. Re...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Patients with oral cancer can develop complications related to the tumor, the treatment, or patient factors. Surgery, radiotherapy, chemotherapy, or some combinations of these treatments are used for oral cancer, depending on the type of cancer, anatomic site, and stage. The major objectives of oral cancer therapy are complete control of the tumor with minimal complications and better quality of life for the patient. The development of acute or long-term toxicities can limit the patient's tolerance to therapy, sometimes leading to a suboptimal treatment schedule, poor patient outcome, increased hospital stays, and higher treatment costs.
Source: Dental Abstracts - Category: Dentistry Tags: Hands On Source Type: research
What are the specific challenges faced by older persons with regards to systemic anti-cancer therapy, and how can we improve cancer therapeutics for this population?Age and Ageing
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news
In this study, the potential for SWNHs to serve as nanotheranostic vehicles is demonstrated through simultaneous delivery of the chemotherapeutic cisplatin from SWNH cone interiors and imaging of the nanoparticle transport to tumor cells using conjugated quantum dots (QDs). Following the formation of cisplatin-modified SWNH-QD (SWNH-QD + cis) hybrids, their characterization by scanning and transmission electron microscopy (STEM, TEM), energy dispersive spectroscopy (EDS), and dynamic light scattering (DLS) were performed to characterize the composite nanoparticles. Drug release profiles and 50% inhibitory concent...
Source: Carbon - Category: Materials Science Source Type: research
CONCLUSION:There has been a continuing increase in the number of studies on therapeutic stem cells and CSC-specific markers for selective diagnosis and therapy of cancer. This review focuses on the current status in the use of normal stem cells and CSCs for targeted cancer therapy. Future direction is also proposed.
Source: Tissue Engineering and Regenerative Medicine - Category: Biotechnology Source Type: research
Publication date: Available online 20 June 2018 Source:Pharmacology & Therapeutics Author(s): Joe Pelt, Sara Busatto, Mauro Ferrari, E. Aubrey Thompson, Kabir Mody, Joy Wolfram Clinically approved cancer therapies include small molecules, antibodies, and nanoparticles. There has been major progress in the treatment of several cancer types over recent decades. However, many challenges remain for optimal use of conventional and nanoparticle-based therapies in oncology including poor drug delivery, rapid clearance, and drug resistance. The antimalarial agent chloroquine has been found to mitigate some of these challenges...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Jefferson Health's Sidney Kimmel Cancer Center is teaming up with the Sarah Cannon Research Institute in a collaboration designed to expand clinical trial offerings to patients in the Philadelphia area. Sarah Cannon, based in Nashville, developed the first community-based drug development program in the country. The organization has conducted more than 300 first-in-human studies and has been a clinical trial leader in the majority of approved cancer therapies over the last decade. Through its net work…
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
Conclusion: Our study showed that the switch of the ovarian cancer cell to a calcifying phenotype in the formation of calcification in ovarian cancer. The calcified phenotypic transformation may inform the new prospective in ovarian cancer therapy.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
Background Albumin-to-Alkaline Phosphatase Ratio (ALB/ALP ratio, AAPR), a newly developed index of liver function, has been rarely discussed about its prognostic value in malignancies. The current study attempted to evaluate the prognostic prediction of AAPR in advanced HCC.Methods 237 advanced HCC patients who refused any standard anti-cancer therapies were retrospectively analyzed. The threshold value of AAPR was determined by receiver operating characteristic (ROC) curve. Univariate analyses using Kaplan-Meier method and log-rank test, and multivariate analysis using Cox proportional hazards regression model were conduc...
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
In the past decades, our knowledge about the relationship between cancer and the immune system has increased considerably. Recent years' success of cancer immunotherapy including monoclonal antibodies (mAbs), cancer vaccines, adoptive cancer therapy and the immune checkpoint therapy has revolutionized traditional cancer treatment. However, challenges still exist in this field. Personalized combination therapies via new techniques will be the next promising strategies for the future cancer treatment direction.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
More News: Cancer | Cancer & Oncology | Cancer Therapy | Clinical Trials | Contracts | Databases & Libraries | Genetics | Mergers and Aquisitions | Partnerships | Pharmaceuticals