Endothelin-2 injures the blood-retinal barrier and macroglial M üller cells:: interactions with angiotensin II, aldosterone, and NADPH oxidase.

In conclusion, Edn2 has detrimental effects on the BRB and Müller cells that involve interactions with the renin-angiotensin aldosterone system and Nox1/4.
PMID: 29248456 [PubMed - as supplied by publisher]

Source: The American Journal of Pathology - December 14, 2017 Category: Pathology Authors: Alrashdi SF, Deliyanti D, Talia DM, Wilkinson-Berka JL Tags: Am J Pathol Source Type: research