Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models

Atsttrin, an engineered protein composed of three tumor necrosis factor receptor (TNFR)-binding fragments of progranulin (PGRN), shows therapeutic effect in multiple murine models of inflammatory arthritis . A...

Source: Arthritis Research and Therapy - December 19, 2017 Category: Rheumatology Authors: Jian-lu Wei, Wenyu Fu, Yuan-jing Ding, Aubryanna Hettinghouse, Matin Lendhey, Ran Schwarzkopf, Oran D. Kennedy and Chuan-ju Liu Tags: Research article Source Type: research