Impaired ventricular filling limits cardiac reserve during submaximal exercise in people with type 2 diabetes

Attenuated increases in ventricular stroke volume during exercise are common in type 2 diabetes and contribute to reduced aerobic capacity. The purpose of this study was to determine whether impaired ventricul...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research

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This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Eating right can help keep your body and mind healthy and extend your quality of life. But some older Americans may face barriers to getting enough nutrients or calories. Many ways aging can affect appetite Physiological changes that come with aging can result in reduced calorie needs, which can lead to decreased food intake and altered body composition, even in healthy older adults. This can be compounded by diminished smell and taste, and changes in hormone levels that affect how quickly you feel full. Depression, lack of independence, and social isolation can make food less appealing, further contributing to a less than...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Healthy Eating Source Type: blogs
ConclusionTea consumption, except for very hot tea, seems generally safe at usual levels of intake, with summary estimates indicating the largest reduction for diverse health outcomes at two to three cups per day. Generally, tea consumption seems more beneficial than harmful in this umbrella review. Randomized controlled trials are further needed to understand whether the observed associations are causal.This article is protected by copyright. All rights reserved
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Review Source Type: research
Publication date: Available online 17 June 2019Source: Genes &DiseasesAuthor(s): Fateme Sadat Eshaghi, Hamideh Ghazizadeh, Sakine Kazami Nooreini, Ameneh Timar, Habibollah Esmaeily, Mehrane Mehramiz, Amir Avan, Majid Ghayour-MobarhanAbstractMetabolic syndrome (MetS) is a clustering of metabolic abnormalities that is associated with increased risk of developing cardiovascular disease and type 2 diabetes. There is growing body of data showing the associations of genetic variants of the genes involved in the PI3K/AKT/mTOR pathway with diabetes and obesity. We aimed to investigate the association between MetS and its compo...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
In conclusions, dairy may be part of a healthy diet; however, additional studies exploring confounding factors are needed to ascertain the potential detrimental effects. PMID: 31199182 [PubMed - as supplied by publisher]
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
Authors: Tanner C, Wang G, Liu N, Andrikopoulos S, Zajac JD, Ekinci EI Abstract ■Metformin is recommended as first-line therapy for type 2 diabetes because of its safety, low cost and potential cardiovascular benefits. ■The use of metformin was previously restricted in people with chronic kidney disease (CKD) - a condition that commonly coexists with diabetes - due to concerns over drug accumulation and metformin-associated lactic acidosis. ■There are limited data from observational studies and small randomised controlled trials to suggest that metformin, independent of its antihyperglycaemic effects, may be ...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
(The Lancet) A personalized active lifestyle program for employees with metabolic syndrome (who are at high risk of heart disease, stroke, and type 2 diabetes) that uses wearable activity trackers, a smartphone app, and face-to-face sessions with exercise coaches, can reduce disease severity in both men and women in various occupations, according to a randomized trial of over 300 workers published in The Lancet Public Health journal.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
A study of twins in Sweden links a 30% higher risk in older age of brain artery blockage, which stroke often follows, to type 2 diabetes in middle age.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news
Conclusion: A delay of GE was associated with an increased incidence of cardiovascular events in diabetic subjects with chronic UGI symptoms. PMID: 31177651 [PubMed - as supplied by publisher]
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
AbstractAimsTo determine the potential risk factors and construct the predictive model of diabetic risk among a relatively low risk middle-aged and elderly Chinese population.MethodsInformation of participants was collected in the Dongfeng-Tongji cohort study, a perspective cohort study of Chinese occupational population. The main outcome was incident type 2 diabetes (T2DM). Based on the conventional risk factors of diabetes, we defined low risk participants without underlying diseases such as coronary heart disease, stroke, cancer, dyslipidemia, hypertension, metabolic syndrome, obesity and family history of diabetes. Tot...
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
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