Whole exome sequencing demonstrates recurrent somatic copy number alterations and sporadic mutations in specialized stromal tumors the prostate

In this study, we performed whole exome sequencing (WES) and fluorescence in situ hybridization (FISH) to explore somatic mutations in 1 low-grade stromal sarcoma, 1 high-grade stromal sarcoma, and 12 STUMPs including 5 cases of degenerative atypia type, 1 myxoid type, 1 phyllodes type, and 5 cases of recently described round cell type.

Source: Human Pathology - December 16, 2017 Category: Pathology Authors: Chin-Chen Pan, Toyonori Tsuzuki, Eiichi Morii, Hiroaki Fushimi, Paul Chih-Hsueh Chen, Jonathan I. Epstein Tags: Original Contribution Source Type: research