Paratrimerins G and H, two prenylated phenolic compounds from the stems of Paramignya trimera

Publication date: February 2018 Source:Phytochemistry Letters, Volume 23 Author(s): Mai Thanh Thi Nguyen, Phu Hoang Dang, Tu Ngoc Nguyen, Linh Thuy Thi Bui, Hai Xuan Nguyen, Tho Huu Le, Truong Nhat Van Do, Nhan Trung Nguyen From the stems of Paramignya trimera (Rutaceae), two new prenylated phenolic compounds, paratrimerins G (1) and H (2), together with 24 known compounds, as well as their α-glucosidase inhibitory activity was examined. Paratrimerins G (1) and H (2) showed moderate inhibitory effect, with the IC50 values of 89.2 and 58.8μM, respectively. The plausible biosynthetic pathways of two new compounds was proposed. Graphical abstract

Source: Phytochemistry Letters - December 16, 2017 Category: Chemistry Source Type: research