Fe-doped brushite bone cements with antibacterial property

Publication date: 15 March 2018 Source:Materials Letters, Volume 215 Author(s): Guangda Li, Nan Zhang, Santuan Zhao, Kaili Zhang, Xiaoyu Li, Aihua Jing, Xinping Liu, Tian Zhang In present research, Fe-doped brushite bone cements were synthesized. The setting time, microstructure and antibacterial property of samples were investigated. The results showed that the setting time of cements was retarded to about 20 min and 123 min, respectively, as iron doping content increasing from 1 mol% to 5 mol% in β-TCP powder. Moreover, Fe-doped cements had much bigger crystal particles and calcium iron phosphate was identified in them. Furthermore, Fe-doped cements performed well in inhibiting the growth of Staphylococcus aureus and Pseudomonas aeruginosa, and larger inhibition halo was obtained with more iron content. Nevertheless, the Fe-loaded cements were not so sensitive to Escherichia coli as to the other two bacteria.
Source: Materials Letters - Category: Materials Science Source Type: research