A historical snapshot of Ixodes scapularis-borne pathogens in New Jersey ticks reflects a changing disease landscape

Publication date: Available online 15 December 2017 Source:Ticks and Tick-borne Diseases Author(s): Andrea Egizi, Vivien Roegner, Ary Faraji, Sean P. Healy, Terry L. Schulze, Robert A. Jordan Historical specimens, when available, can provide new insight into the distribution and evolution of pathogens that may not be discernible from more recent samples. We used ticks collected from hunter-killed white-tailed deer in New Jersey in 2002 to examine the prevalence and distribution of four pathogens transmitted by Ixodes scapularis, the blacklegged tick. Infection with Borrelia burgdorferi sensu stricto, Babesia microti, and Anaplasma phagocytophilum (the agents of Lyme disease, human babesiosis, and human granulocytic anaplasmosis, respectively) was highest in the Coastal Plain and lowest in the northwestern Skylands region.These patterns correspond well with the historically observed northward expansion of I. scapularis within New Jersey and the comparatively recent increase in human cases of these pathogens in the northern part of the state. Additionally, we provide evidence that Borrelia miyamotoi, a relatively new emerging pathogen and agent of relapsing fever, was widespread (though not common) throughout the state in 2002. Our findings highlight the need for enhanced awareness of tick-borne diseases other than Lyme and implementation of large-scale tick surveillance in endemic regions.
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research

Related Links:

We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the mother-fetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in pregnancy.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSIONS: Our data highlight the lack of research on congenital CD.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSIONS: This study shows low circulation of antibodies to R. rickettsii in CVL-seropositive dogs. It is recommended that surveillance studies in dogs should continue in order to monitor this scenario.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Publication date: Available online 20 February 2019Source: Preventive Veterinary MedicineAuthor(s): S. Patterson, K. Bond, M. Green, S. van Winden, J. GuitianAbstractJohne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic condition of dairy cattle, and is endemic in the UK. Lack of understanding of the relative importance of different transmission routes reduces the impact of control scheme recommendations. The long incubation period for Johne’s disease makes evaluation of control schemes difficult, and so this long-term cohort study offers a rare and valuable insight into the...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
In this study, after implementing the intervention using the PRECEDE educational program, asignificant difference was found between the intervention and control groups in the mean scores for predisposing factors (knowledge and attitude) (P
Source: Pathogens and Global Health - Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research
Publication date: Available online 20 February 2019Source: Phytochemistry LettersAuthor(s): Grażyna Łaska, Elwira Sieniawska, Łukasz Świątek, Jordan Zjawiony, Shabana Khan, Anastazja Boguszewska, Marcin Stocki, Mirosław Angielczyk, Małgorzata Polz-DacewiczAbstractPolemonium caeruleum L. is a Chinese medicinal plant used in the treatment of tuberculosis, whooping cough, fever, infertility, epilepsy, endometritis and insomnia. It was also used as sedative and anaesthetic agent. In this work the phytochemical investigation using LC-ESI-QTOF-MS and GC–MS techniques was done for chemical characterization of methano...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
In this study, we aimed to update the estimations of case-fatality ratios for measles, to develop a prediction model to estimate case-fatality ratios across heterogeneous groupings, and to project future case-fatality ratios for measles up to 2030.MethodsWe did a review of the literature to identify studies examining measles cases and deaths in low-income and middle-income countries in all age groups from 1980 to 2016. We extracted data on case-fatality ratios for measles overall and by age, where possible. We developed and examined several types of generalised linear models and determined the best-fit model according to t...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
This study aimed to quantify the economic impact of pre-existing opioid dependency in patients undergoing lower extremity bypass surgery.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Abstract from the 2019 Society for Clinical Vascular Surgery Annual Symposium Source Type: research
Contributors : Jian-Da Lin ; Hitoo Nishi ; Jordan Poles ; Xiang Niu ; Emily J Brown ; Stephen A Ramsey ; Edward A Fisher ; P'ng LokeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn atherosclerosis progression and regression, monocytes or monocyte-derived macrophages are the major immune cells in the plaque. It is important to understand the fate and characteristics of monocyte/macrophage during the plaque progression and regression. To characterize the fate of monocytes/macrophages, we performed single cell RNA sequencing of fate-mapped aortic CX3CR1-derived monocytes/macrophages fr...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Publication date: Available online 5 August 2015 Source:Ticks and Tick-borne Diseases Author(s): Marten J. Edwards, Laura A. Barbalato, Amulya Makkapati, Katerina D. Pham, Louise M. Bugbee Several human pathogens are transmitted by the blacklegged tick, Ixodes scapularis. These include the spirochetes that cause Lyme disease (Borrelia burgdorferi) which is endemic to the Lehigh Valley region of eastern Pennsylvania. Emerging and currently rare tick-borne diseases have been of increasing concern in this region, including tick-borne relapsing fever (caused by Borrelia miyamotoi), human granulocytic anaplasmosis (cause...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
More News: Anaplasmosis | Babesiosis | Borrelia | Endemics | History of Medicine | Jordan Health | Lyme Disease | Middle East Health | Tickborne Diseases | Zoology