Novel treatment strengthens bones in genetic disease neurofibromatosis type-1

(Vanderbilt University Medical Center) An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.The researchers demonstrated in a mouse model of the disorder that the enzyme asfotase-alpha improves bone growth, mineralization and strength. Their findings are published in the August issue of Nature Medicine.
Source: EurekAlert! - Biology - Category: Biology Source Type: news