Ohio moves to ban abortions for Down syndrome

Bill could face legal challenges if Gov. John Kasich signs it into law
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news

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(Boston University School of Medicine) Tarik F. Haydar, PhD, professor of anatomy and neurobiology at Boston University School of Medicine (BUSM), has been awarded a two-year Exploratory/Developmental Research Grant Award (R21) from the National Institutes of Health (NIH).
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
INTRODUCTION: Core stability exercises and treadmill training play a crucial role in physical therapy interventions and have an effect on balance in children with Down Syndrome (DS); however, whether core stability exercises or treadmill training has more ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Publication date: Available online 11 July 2019Source: Cancer CellAuthor(s): Maurice Labuhn, Kelly Perkins, Sören Matzk, Leila Varghese, Catherine Garnett, Elli Papaemmanuil, Marlen Metzner, Alison Kennedy, Vyacheslav Amstislavskiy, Thomas Risch, Raj Bhayadia, David Samulowski, David Cruz Hernandez, Bilyana Stoilova, Valentina Iotchkova, Udo Oppermann, Carina Scheer, Kenichi Yoshida, Adrian Schwarzer, Jeffrey TaubSummaryMyeloid leukemia in Down syndrome (ML-DS) clonally evolves from transient abnormal myelopoiesis (TAM), a preleukemic condition in DS newborns. To define mechanisms of leukemic transformation, we combin...
Source: Cancer Cell - Category: Cancer & Oncology Source Type: research
Autoimmune thyroid diseases (AITDs), including Hashimoto’s thyroiditis (HT) and Graves’ disease (GD), tend to aggregate with other non-thyroidal autoimmune diseases (NTADs). Aim of this Mini-review is to report the most recent insights concerning the clustering of NTADs in pediatric patients with either HT or GD, the pathophysiology of AITDs and the metamorphic thyroid autoimmunity. A systematic literature research of the last fifteen years, according to EQUATOR statement, was carried out through MEDLINE via PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) Embase, CINAHL, Cochrane Library, based on the following ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
ConclusionsCore stability and treadmill training improved balance in children with Down Syndrome and should be applied in conjunction with physical therapy programs.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
(University of Oxford) Researchers at the University of Oxford, in collaboration with colleagues from Hannover Medical School and Martin-Luther-University Halle-Wittenberg, have discovered the specific gene mutations that are required for the development of leukaemia in children with Down's syndrome.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
(University of Oxford) Researchers at the University of Oxford, in collaboration with colleagues from Hannover Medical School and Martin-Luther-University Halle-Wittenberg, have discovered the specific gene mutations that are required for the development of leukemia in children with Down syndrome.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Leukemia, Published online: 11 July 2019; doi:10.1038/s41375-019-0514-9Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome
Source: Leukemia - Category: Hematology Authors: Source Type: research
Abstract Alternative splicing of pre-mRNA is a major mechanism to diversify protein functionality in metazoans from a limited number of genes. In the Drosophila Down Syndrome Cell Adhesion Molecule (Dscam) important for neuronal wiring up to 38,016 isoforms can be generated by mutually exclusive alternative splicing in four clusters of variable exons. However, it is not understood how a specific exon is chosen from the many variables and how variable exons are prevented from being spliced together. A main role in the regulation of Dscam alternative splicing has been attributed to RNA binding proteins, but how they...
Source: RNA - Category: Genetics & Stem Cells Authors: Tags: RNA Source Type: research
Publication date: Available online 8 July 2019Source: Genes &DiseasesAuthor(s): Hui Zhang, Lingjuan Liu, Jie TianAbstractDown syndrome (DS), as a typical genomic aneuploidy, is a common cause of various birth defects, among which is congenital heart disease (CHD). 40-60% neonates with DS have some kinds of CHD. However, the molecular pathogenic mechanisms of DS associated CHD are still not fully understood. This review summarizes available studies on DS associated CHD from seven aspects so as to provide a crucial and updated overview of what we known so far in this domain.
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
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